Adolescence is a developmental period frequently characterized by impulsive behavior and suboptimal decision making, aspects that often result in increased rates of substance abuse, unprotected sex, and several other harmful behaviors. Functional magnetic resonance imaging (fMRI) studies have attempted to reveal the brain mechanisms that underlie the typical inhibitory control limitations associated with this developmental period. In the present review, all available studies in the PsycINFO, PubMed, and Web of Science databases that investigated this issue utilizing fMRI were analyzed. In contrast to adults, adolescents exhibited decreased activity in several brain regions associated with inhibitory control such as the dorsolateral prefrontal cortex, anterior cingulate cortex, and fronto-striatal regions. The decreased activity found in these regions may underlie the diminished inhibitory control abilities associated with this development period.
inhibitory control; development; adolescence; fMRI; anti-saccade; Go/No-go
