Characterization of pin blends Poly (L-co-D,L lactic acid) /Poly(caprolactone diol) (PLDLA/PCL-T) and analysis of mechanical property of pins during in vitro degradation

Abstract

The bone fixation devices, conventional metallic cranium used in surgery have presented some problems, such as corrosion, inflammation and infection, and a lower mechanically newly formed bone structure due to the atrophy caused by the difference in stiffness between metal and bone. These reasons have led to increased interest in bioreabsorbable polymeric devices. The most bioresorbable polymers used in this application belong to the family of poly (α-hydroxy acids), which are characterized degrade by hydrolysis of its ester linkages, such as copolymer poly (L-lactic acid-co-D, L lactic acid) (PLDLA). In this work was investigated some effects of the addition poly (caprolactone triol), PCL-T in the PLDLA. Pins were prepared by melting in the 100/0, 90/10, 70/30 and 50/50 (w/w) compositions, PLDLA/PCL-T. The pins were characterized by different methods (DSC, SEM and mechanical test). The in vitro pins degradation was investigated. It was observed that the addition of PCL-T of PLDLA modifies the mechanical properties, morphological, we conclude that PLDLA/PCL-T can be a potential material for various applications, where the question of flexibility to make necessary.

Keywords:
PLDLA/PCL-T; characterization; mechanical properties; in vitro