Pt(II) and Ag(I) complexes with acesulfame: crystal structure and a study of their antitumoral, antimicrobial and antiviral activities, Cavicchioli et al. (2010)1212 Cavicchioli, M.; Massabni, A. C.; Heinrich, T. A.; Costa-Neto, C. M.; Abrão, E. P.; Fonseca, B. A. L.; Castellano, E. E.; Corbi, P. P.; Lustri, W. R.; Leite, C. Q. F.; J. Inorg. Biochem. 2010, 104, 533.
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acesulfame (ace), C4H4KNO4S |
[Ag(C4H4NO4S)]n
|
n/s (3.1)†
|
6-Mercaptopurine complexes with silver and gold ions: Anti-tuberculosis and anti-cancer activities, Cuin et al. (2011)1313 Cuin, A.; Massabni, A. C.; Pereira, G. A.; Leite, C. Q. F.; Pavan, F. R.; Sesti-Costa, R.; Heinrich, T. A.; Costa-Neto, C. M.; Biomed. Pharmacother. 2011, 5, 334.
|
6-mercaptopurine, C5H4N4S |
(Ag[C5H3N4S])∙H2O |
25.0 (93.2) |
A broad study of two new promising antimycobacterial drugs: Ag(I) and Au(I) complexes with 2-(2-thienyl)benzothiazole, Pereira et al. (2012)1414 Pereira, G. A.; Massabni, A. C.; Castellano, E. E.; Costa, L. A. S.; Leite, C. Q. F.; Pavan, F. R.; Cuin, A.; Polyhedron 2012, 38, 291.
|
2-(2-thienyl)benzothiazole, C11H7NS2
|
[Ag(C11H7NS2)2NO3] |
12.5 (20.7) |
Synthesis, crystal structures, antimicrobial, antifungal and antituberculosis activities of mixed ligand silver(I) complexes, Altaf et al. (2013)1515 Altaf, M.; Stoeckli-Evans, H.; Cuin, A.; Sato, D. N.; Pavan, F. R.; Leite, C. Q. F.; Ahmad, S.; Bouakka, M.; Mimouni, M.; Khardli, F. Z.; Hadda, T. B.; Polyhedron 2013, 62, 138.
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(P1): triphenyl phosphine (P2): tricyclohexyl phosphine (P3): phenyldicyclohexyl phosphine (P4): diphenylcyclohexyl phosphine (P5): diphenyl(p-tolyl) phosphine
(L1): thiosemicarbazide (L2): 2-(propan-2-ylidene)hydrazinecarbothioamide (L3): 4,5-dihydrothiazole-2-thiol (A) or thiazolidine-2-thione (B) |
1 = [Ag2(P1)2(L1)4](NO3)∙2H2O 2 = [Ag2(P1)2(L3)4](NO3)2 3 = [Ag(P2)(L3)2](NO3) 4 = [Ag(P2)(L1)2]PF6 5 = [Ag(P3)2(L2)]2(NO3)}NO3 6 = [Ag2(P2)2(L3)2](PF6)2 7 = [Ag2(P4)2(L2)2](ClO4)2 8 = [Ag(P5)2(L2)(Br)] 9 = [Ag2(P1)2(L2)2](NO3)2
|
1 = 10.2 (8.1) 2 = 15.6 (11.6) 3 = 10.6 (14.7) 4 = 10.6 (14.2) 5 = 12.5 (7.35) 6 = 7.8 (6.0) 7 = 12.5 (10.3) 8 = 12.5 (14.3) 9 = 10.2 (9.0) |
Silver(I) complexes with symmetrical Schiff bases: Synthesis, structural characterization, DFT studies and antimycobacterial assays, Paiva et al. (2013)1616 Paiva, I. L.; Carvalho, G. S. G.; Silva, A. D.; Corbi, P. P.; Bergamini, F. R. G.; Formiga, A. L. B.; Diniz, R.; Carmo, W. R.; Leite, C. Q. F.; Pavan, F. R.; Cuin, A.; Polyhedron 2013, 62, 104.
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MBDA = N,N’-bis[(4-methoxyphenyl)methylidene]ethane-1,2-diamine, C18H20N2O2 MBDB = N,N’-bis[(4-methoxyphenyl)methylidene]propane-1,3-diamine, C19H22N2O2
|
AgMBDA = [Ag(C18H20N2O2)2]NO3
AgMBDB = [Ag(C19H22N2O2)NO3]∙½H2O |
AgMBDA = 21.2 (27.8)
AgMBDB = 11.3 (23.5) |
Synthesis and biological evaluation of ternary silver compounds bearing N,N-chelating ligands and thiourea: X-ray structure of [{Ag(bpy)(μ-tu)}2](NO3)2 (bpy = 2,2′-bipyridine; tu = thiourea), Segura et al. (2014)1717 Segura, D. F.; Netto, A. V. G.; Frem, R. C. G.; Mauro, A. E.; Silva, P. B.; Fernandes, J. A.; Paz, F. A. A.; Dias, A. L. T.; Silva, N. C.; Almeida, E. T.; Marques, M. J.; Almeida, L.; Alves, K. F.; Pavan, F. R.; Souza, P. C.; Barros, H. B.; Leite, C. Q. F.; Polyhedron 2014, 79, 197.
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phen = 1,10-phenanthroline bpy = 2,20-bipyridine tu = thiourea |
1 = [{Ag(phen)(m-tu)}2](NO3)2 C26H24Ag2N10O6S2 2 = [{Ag(phen)(m-tu)}2](CF3SO3)2 C28H24Ag2F6N8O6S4 3 = [{Ag(bpy)(m-tu)}2](NO3)2 C22H24Ag2N10O6S2 |
1 = 4.7 ± 0.4 (11.0 ± 1.0) 2 = 7.3 ± 1.4 (14.2 ± 2.8) 3 > 25 |
Coordinative versatility of a Schiff base containing thiophene: Synthesis, characterization and biological activity of zinc (II) and silver (I) complexes, Silva et al. (2014)1818 Silva, S. A.; Leite, C. Q. F.; Pavan, F. R.; Masciocchi, N.; Cuin, A.; Polyhedron 2014, 79, 170.
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ThioEn = N,N′-bis(thiophen-2-ylmethylene)ethane-1,2-diamine |
1 = [Ag(ThioEn)]NO3 2 = [Ag(ThioEn)2]NO3
|
1 = 12.2 (29.2) 2 = 24.5 (36.7) |
A silver complex with cycloserine: synthesis, spectroscopic characterization, crystal structure and in vitro biological studies, Ciol et al. (2018)1919 Ciol, M. R.; Manzano, C. M.; Cuin, A.; Pavan, F. R.; Ribeiro, C. M.; Ruiz, A. L. T. G.; Oliveira, E. C. S.; Lustri, W. R.; Fregonezi, N. F.; Nogueira, F. A. R.; Corbi, P. P.; ChemistrySelect 2018, 3, 1719.
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cycloserine, C3H6N2O2
|
[AgC3H5N2O2] |
16.5 ± 0.6 (79.1) |
Silver(I) and zinc(II) complexes with symmetrical cinnamaldehyde Schiff base derivative: Spectroscopic, powder diffraction characterization, and antimycobacterial studies, Amaral et al. (2018)2020 Amaral, T. C.; Miguel, F. B.; Couri, M. R. C.; Corbi, P. P.; Carvalho, M. A.; Campos, D. L.; Pavan, F. R.; Cuin, A.; Polyhedron 2018, 146, 166.
|
N,N’-bis(trans-cinnamaldehyde)ethane-1,2-diamine C20H20N2
|
[C20H20AgN3O3] |
10.4 (22.7) |
Enhancement in anti-tubercular activity of indole based thiosemicarbazones on complexation with copper(I) and silver(I) halides: Structure elucidation, evaluation and molecular modelling, Khan et al. (2018)2121 Khan, A.; Jasinski, J. P.; Smolenski, V. A.; Hotchkiss, E. P.; Kelley, P. T.; Shalit, Z. A.; Kaur, M.; Paul, K.; Sharma, R., Bioorg. Chem. 2018, 80, 303.
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thiosemicarbazones (H 1L, H 2L, H 3L) + phosphine |
13 = [AgCl(η1-S-HIntsc)(Ph3P)2] 14 = [AgBr(η1-S-HIntsc)(Ph3P)2] 15 = [AgCl(η1-S-HIntsc-N1-Me)(Ph3P)2] 16 = [AgBr(η1-S-HIntsc-N1-Me)(Ph3P)2] 17 = [AgCl(η1-S-5-MeOHIntsc)(Ph3P)2] 18 = [AgBr(η1-S-5-MeOHIntsc)(Ph3P)2] |
13 = 1.6 (n/s)†† 14 = 6.3 (n/s) 15 = 1.6 (n/s) 16 = 1.6 (n/s) 17 = 1.6 (n/s) 18 = 1.6 (n/s) |
Synthesis and antimicrobial activity of a phenanthroline-isoniazid hybrid ligand and its Ag+ and Mn2+ complexes, Ahmed et al. (2019)2222 Ahmed, M.; Rooney, D.; McCann, M.; Devereux, M.; Twamley, B.; Galdino, A. C. M.; Sangenito, L. S.; Souza, L. O. P.; Lourenço, M. C.; Gomes, K.; Santos, A. L. S.; BioMetals 2019, 32, 671.
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L = (Z)-N’-(6-oxo-1,10-phenanthrolin-5(6H)-ylidene)isonicotinohydrazide |
1 = [Ag(L)2]NO3∙2H2O [Ag(C18H11N5O2)2]NO3∙2H2O
2 = [Ag(L)2]BF4 [Ag(C18H11N5O2)2]BF4
|
1 = 2.5 (2.9)
2 = 2.5 (2.9) |
Silver complexes with fluoroanthranilic acid isomers: spectroscopic characterization, antimycobacterial activity and cytotoxic studies over a panel of tumor cells, Manzano et al. (2019)2323 Manzano, C. M.; Nakahata, D. H.; Tenorio, J. C.; Lustri, W. R.; Nogueira, F. A. R.; Aleixo, N. A.; Gomes, P. S. S.; Pavan, F. R.; Grecco, J. A.; Ribeiro, C. M.; Corbi, P. P.; Inorg. Chim. Acta 2020, 502, 119293.
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fluoroanthranilic acid C7H6FNO2
|
[Ag(C7H6FNO2)2]+ isomers (4fa, 5fa and 6fa) |
Ag4fa = 2.6 ± 0.1 (9.8 ± 0.5) Ag5fa = 4.2 ± 2.2 (15.9 ± 8.6) Ag6fa = 2.6 ± 3.1 (9.8 ± 11.9) |
Cytotoxic and apoptotic effects of ternary silver (I) complexes bearing 2-formylpyridine thiosemicarbazones and 1,10-phenanthroline, Silva et al. (2020)2424 Silva, D. E. S.; Becceneri, A. B.; Solcia, M. C.; Santiago, J. V. B.; Moreira, M. B.; Gomes Neto, J. A.; Pavan, F. R.; Cominetti, M. R.; Pereira, J. C. M.; Netto, A. V. G.; Dalton Trans. 2020, 49, 5264.
|
2-formylpyridine-N(4)-R-thiosemicarbazones (L) and 1,10-phenanthroline (phen) |
1 = [Ag(phen)(PHTSC)](NO3)∙HCl∙2H2O C19H21AgClN7O5S 2 = [Ag(phen)(PMTSC)](NO3)∙HCl∙CH3OH C21H23AgClN7O4S 3 = [Ag(phen)(PETSC)](NO3)∙HCl∙2H2O C21H25AgClN7O5S
|
1 = 2.4 ± 0.4 (4.0 ± 0.6)
2 = 2.3 ± 0.3 (3.8 ± 0.5)
3 = 2.6 ± 0.2 (4.0 ± 0.4) |
Copper(I) and silver(I) complexes of anthraldehyde thiosemicarbazone: Synthesis, structure elucidation, in vitro anti-tuberculosis/cytotoxicity activity and interactions with DNA/HSA, Khan et al. (2020)2525 Khan, A.; Paul, K.; Singh, I.; Jasinski, J. P.; Smolenski, V. A.; Hotchkiss, E. P.; Kelley, P. T.; Shalit, Z. A.; Kaur, M.; Banerjee, S.; Roy, P.; Sharma, R.; Dalton Trans. 2020, 49, 17350.
|
9-anthraldehyde thiosemicarbazone and phosphine |
4 = Ag2(μ2-Cl)2(η1-S-9-Hanttsc)2(Ph3P)2] C68H56Cl2Ag2N6P2S2 5 = [Ag2(μ2-Br)2(η1-S-9-Hanttsc)2(Ph3P)2] C68H56Br2Ag2N6P2S2 9 = [Ag2Cl2(μ2-S-9-Hanttsc-N1-Me)2(Ph3P)2] C70H60Cl2Ag2N6P2S2 10 = Ag2Br2(μ2-S-9-Hanttsc-N1-Me)2(Ph3P)2] C70H60Br2Ag2N6P2S2
|
4 = 1.6 (n/s)†† 5 = 1.6 (n/s) 9 = 12.5 (n/s) 10 = 12.5 (n/s) |
(Amino)cyclophosphazenes as multisite ligands for the synthesis of antitumoral and antibacterial silver(I) complexes, Gascón et al. (2020)2626 Gascón, E.; Maisanaba, S.; Otal, I.; Valero, E.; Repetto, G.; Jones, P. G.; Jiménez, J.; Inorg. Chem. 2020, 59, 2464.
|
(amino)cyclophosphazenes and phosphine |
2 = [N3P3(NHCy)6{AgPPh3}2](TfO)2 3 = [N3P3(NHCy)6{AgPPh3}3](TfO)3 4 = [N3P3(NHCy)6{AgPPh2Me}2](TfO)2 5 = [N3P3(NHCy)6{AgPPh2Me}3](TfO)3 6 = [N3P3(NHCy)6{AgTPA}3](TfO)3 9 = [N3P3(NHCy)3(NMe2)3{AgPPh2Me}2](TfO)2 10 = [N3P3(NHCy)3(NMe2)3{AgPPh2Me}3](TfO)3
|
2 = n/s (3.9)† 3 = n/s (0.97) 4 = n/s (3.9) 5 = n/s (3.9) 6 = n/s (3.9) 9 = n/s (3.9) 10 = n/s (3.9) |
Antibacterial activities and antiproliferative assays over a tumor cells panel of a silver complex with 4-aminobenzoic acid: Studies in vitro of sustained release using bacterial cellulose membranes as support, Aquaroni et al. (2020)2727 Aquaroni, N. A. S.; Nakahata, D. H.; Lazarini, S. C.; Resende, F. A.; Cândido, A. L. P.; Barud, H. S.; Claro, A. M.; Carvalho, J. E.; Ribeiro, C. M.; Pavan, F. R.; Lustri, B. C.; Ribeiro, T. R. M.; Moreira, C. G.; Cândido, T. Z.; Lima, C. S. P.; Ruiz, A. L. T. G.; Corbi, P. P.; Lustri, W. R.; J. Inorg. Biochem. 2020, 212, 111247.
|
4-aminobenzoic acid, C7H7NO2
|
[Ag(C7H7NO2)2(NO3)] |
12.7 (28.5 ± 6.6) |
Synthesis, characterization, DFT modeling and in vitro antimycobacterial activity assays of a silver(I)-isoniazid complex, Paris Junior et al. (2021)2828 Paris Junior, J. A.; Cavicchioli, M.; Machado, R. T. A.; Pavan, F. R.; Nakahata, D. H.; Corbi, P. P.; Costa, A. M. F.; Pereira, D. H.; Massabni, A. C.; Quim. Nova 2021, 44, 278.
|
isoniazid, C6H7N3O |
[AgC6H7N3O]NO3. |
0.8 + 0.5 (2.6) |
Chemical, spectroscopic characterization, molecular modeling and antibacterial activity assays of a silver (I) complex with succinic acid, Paris Junior et al. (2021)2929 Paris Junior, J. A.; Rocchi, A. J. S.; Biagioni, B. T.; Cavicchioli, M.; Machado, R. T. A.; Pavan, F. R.; Corbi, P. P.; Lustri, W. R.; Pereira, D. H.; Massabni, A. C.; Eclet. Quim. J. 2021, 46, 26.
|
succinic acid, C4H6O4
|
Ag2C4H4O4
|
n/s (23.9)†
|
Promising Ag(I) complexes with N-acylhydrazones from aromatic aldehydes and isoniazid against multidrug resistance in tuberculosis, Santos et al. (2021)3030 Santos, P. V. P.; Ribeiro, C. M.; Pavan, F. R.; Corbi, P. P.; Bergamini, F. R. G.; Carvalho, M. A.; D’Oliveria, K. A.; Cuin, A. J.; Mol. Struct. 2021, 1234, 130193.
|
N-acylhydrazones + isoniazid * |
1 = AgIZSAL [Ag(C13H11N3O2)2(H2O)]NO3 2 = AgIZoVA [Ag(C14H13N3O3)2NO3]∙H2O 3 = AgIZmVA [Ag(C14H13N3O3)]NO3 4 = AgIZVAN [Ag(C14H13N3O3)2]NO3
|
1 = 11.56 ± 0.90 (17.24) 2 > 25 (> 34.23) 3 > 25 (> 56.67) 4 > 25 (> 35.09) |