Dornellas et al. 2000 |
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USA
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Unicentric
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Feb. 1996 Jan. 1997
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|
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Single group (n = 54)
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• Bedside counseling during hospitalization (20 minutes) and post-discharge telephone counseling, with calls at 1, 4, 8, 12, 16, 20, 26 weeks post-discharge
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Self-reported abstinence for 7 days and confirmed by cohabiting, 6 and 12 months after discharge
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Results
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There was a difference between the groups
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• 6 months:
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- Intervention group = 67%
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- Control group = 43% (p <0.05)
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• 12 months:
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- Intervention group = 55%
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- Control Group = 34% (p <0.05)
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Hennrikus et al. 2005 |
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Group 1 (n = 703)
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• Modified standard care and note highlighted in the patient's record, recommending advice by the assistant team
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Group 2 (n = 696)
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• Modified standard care, note highlighted in the medical record and additional telephone counseling sessions
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- ≥ 1 - 617 (90%)
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- ≥ 4- 318 (63%)
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- ≥ 7 -88 (13%)
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• Outcome 1: Self-reported abstinence for 7 days, 7 days post-discharge
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• Outcome 2: Self-reported abstinence for 7 days, 12 months after discharge
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• Outcome 3: Abstinence for 7 days, 12 months after discharge confirmed by salivary cotinine
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Results
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There was a difference in relation to outcome 2
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• Outcome 1:
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- Group 1 = 24%;
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- Group 2 = 25.2%
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- Control group = 26%
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- (p> 0.05)
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• Outcome 2:
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- Group 1 = 15.2%
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- Group 2 = 19.8%
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- Control group = 15%
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- (p <0.05).
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• Outcome 3:
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- Group 1 = 10%
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- Group 2 = 9.9%
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- Control group = 8.8%
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- (p> 0.05)
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Reid et al. 2007 |
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Canada
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Pilot Unicentric
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Nov. 2004 May 2015
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Self-reported abstinence in the last 7 days, 52 weeks after discharge
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Results
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There was no difference between groups Intervention group = 46% Control group = 34.7% (p = 0.25)
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Regan et al. 2011 |
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USA
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Unicentric
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Dec. 2007 Jul. 2008
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Self-report of cessation 2 and 12 weeks after discharge
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Results
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There was no difference between the groups studied
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• Withdrawal 2 weeks after discharge
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- Intervention group = 39%
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- Control group = 39%
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- RR 1.02
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- CI = 0.85–1.22
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• Abstinence 12 weeks after discharge
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- Intervention group = 29%
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- Control group = 26%
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- RR 1.11
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- CI = 0.9–1.41
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Rigotti et al. 2014 |
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USA
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Unicentric
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Aug. 2010 Apr. 2012
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397
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Smokers hospitalized for multiple causes that:
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• Received counseling during hospitalization
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• Planned to quit smoking
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• Accepted the pharmacological treatment
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Single group (n = 198)
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• Medication for 30 days, with replacement twice for up to 90 days, 5 IVR (2, 14, 30, 60 and 90 days after discharge) and fax to the primary care physician informing about the treatment
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Biochemically proven abstinence for 7 days, 6 months after discharge (cotinine, or monoxymetry for those using NRT), self-reported abstinence for 7 days and abstinence continues 2.3 and 6 months after discharge
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Results
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There was a difference between the groups in the main outcome and in some secondary outcomes
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• Biochemically proven withdrawal:
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- Intervention group = 26%
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- Control group = 15%
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- (p = 0.009)
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• Self-reported abstinence last 7 days 6 months after discharge:
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- Intervention group = 40.9%
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- Control group = 28.1%
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- (p = 0.008)
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• Continuous self-reported abstinence 6 months after discharge:
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- Intervention group = 27.3%
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- Control group = 16.1%
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- (p = 0.007)
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• Other outcomes without statistically significant difference between groups
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Cummins et al. 2016 |
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USA
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Multicenter
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Jun. 2011 Nov. 2013
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Self-reported abstinence for 7 and 30 days, 2 and 6 months after discharge, and salivary cotinine-confirmed abstinence in those who reported abstinence for 7 days, 6 months after discharge.
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Result
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There was no difference between the intervention groups and the control group or between the different intervention groups in any of the analyzed outcomes Main outcome:
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• Abstinence for 30 days, 6 months after discharge:
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- Groups without patches = 18.3%
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- Groups with patches = 22.8%
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- (p = 0.051)
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• Counseling groups = 21.1%
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• Groups without counseling = 20.0%
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• (p = 0.65)
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Fellows et al. 2016 |
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USA
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Multicenter
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Nov. 2011 Nov. 2013
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Single group (n = 597)
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• Approach during hospitalization
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• Proactive reference for post discharge assistance
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• Pharmacotherapy (offered according to a health plan) and 4 IVR 4, 14, 28 and 49 days after discharge
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(n = 301)
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• Approach during hospitalization
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• Standard care after discharge:
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- Information on medications and how to access quitline.
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- A brief follow-up call to assess cessation
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Self-reported abstinence in the last 30 days, 6 months after randomization
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Result:
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There was no difference in cessation between the two groups in the primary or secondary outcomes related to cessation
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• Intervention group = 24%
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• Control group = 22%
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• (p = 0.159)
|
Harrington et al. 2016 |
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USA
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Unicentric
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Jul. 2011 May 2013
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(n = 740)
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• Standard care
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Self-reported abstinence for 30 days, 6 months after discharge
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Results:
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There was no difference between groups
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• Intervention group = 25.8%
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• control group = 24.1%
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• (p = 0.436)
|
Sherman et al. 2016 |
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1,619
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Smokers hospitalized for multiple causes, with a high number of participants on the street or in temporary housing (25%) alcohol users (40%), and with mental illness (50%) and use of other drugs (60%)
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Single group (n = 805)
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• Post-discharge counseling calls (proactive), 2 weeks after discharge, other calls 1, 3, 7, 14, 30 and 42 days after the first call
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Self-reported abstinence for 30 days, 2 and 6 months after discharge
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Results:
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There was a difference between the groups
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• Withdrawal 2 months after discharge:
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- Intervention group = 29.0%
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- Control group = 20.7%
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- (RR 1.40 CI = 1.13, 1.73)
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• Withdrawal 6 months after discharge:
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- Intervention group = 37.4%
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- Control group = 32.5%
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- (RR 1.19 CI = 1.01, 1.40)
|
Richter et al. 2016# |
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USA
-
Multicenter
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Jul. 2011 Out. 2014
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|
|
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• Abstinence in the last 7 days, self-reported, 6 months after discharge
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• Biochemically confirmed abstinence (cotinine, carbon monoxide, proxy) 6 months after discharge
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Results
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There was no difference between the groups studied
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• Self-reported abstinence for 7 days, 6 months after discharge:
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- Intervention group = 25.4%
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- Control group = 25.3%
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- (p = 0.88)
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• Abstinence confirmed for 7 days 6 months after discharge (carbon monoxide and cotinine):
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- Intervention group = 23.7%
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- Control group = 21.6%
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- Oradj = 1.02
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- 95% CI = 0.77, 1.35
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- (p = 0.88)
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- RR = 1.02
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- 95% CI = 0.82; 1.24
|
Rigotti et al. 2016 |
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USA
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Multicenter
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Dec. 2012 Jul. 2014
|
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1,359
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Smokers hospitalized for multiple causes who:
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• Received counseling at hospitalization
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• Planned to quit smoking
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• Accepted the pharmacological treatment
|
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Single group (n = 681)
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• Medication for 30 days, with replacement twice for up to 90 days, 5 IVR (2, 12, 28, 58 and 88 days after discharge) and possibility to access a counselor if necessary
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|
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Biochemically proven abstinence for 7 days, 6 months after discharge (cotinine or monoxymetry for those using NRT) Self-report abstinence assessment at 1, 3 and 6 months
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Results
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There was a difference between groups in outcome 2
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• Biochemically proven abstinence: - Intervention group = 17%
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- Control group = 16%
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- (p = 0.58)
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• Self-reported abstinence for 7 days, 1 month after discharge:
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- Intervention group = 43%
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- Control group = 32%
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- (p <0.0001)
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• Self-reported abstinence for 7 days, 3 months after discharge:
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- Intervention group = 37%
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- Control group = 30%
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- (p = 0.008)
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• Self-reported abstinence 6 months after discharge:
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- Intervention group = 31%
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- Control group = 27%
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- (p = 0.09)
|
Thomas et al. 2016 |
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Australia
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Multicenter
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Apr. 2012 Jun. 2014
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|
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Single group (n = 300)
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• Behavioral approach (2 sessions in the hospital and 3rd session 4 weeks after discharge). Motivational interview for those who did not want to quit smoking. Pharmacotherapy during hospitalization and 1 week after discharge. Pharmacotherapy for another 28 days according to availability (PBS). Impressive information material, quitline reference, case summary and action plan for assistant physician and community pharmacist and follow-up by telephone at 1, 6 and 12 months after discharge
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(n = 300)
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• Standard care for each hospital: - Brief intervention during hospitalization - Available pharmacotherapy: NRT, bupropion and varenicline maintained for a period of 28 days after discharge according to PBS and follow up by phone at 1, 6 and 12 months after discharge
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-
Abstinence for 30 days, six months after discharge, confirmed with monoxymetry Abstinence for 6 months, 12 months after discharge, also by monoxymetry Self-reported abstinence for 30 days at 1, 6 and 12 months
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Results
-
There was no difference between groups
-
• Abstinence for 30 days, six months after discharge, confirmed with monoxymetry:
-
- Intervention group = 11.6%
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- Control group = 12.6%
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- (OR) = 0.91
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- 95% (CI) = 0.55–1.50
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• Abstinence for 30 days, 12 months after discharge, confirmed with monoxymetry
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- Intervention group = 11.6%
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- Control group = 11.2%
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- OR = 1.04
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- 95% CI = 0.63–1.73
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• Self-reported abstinence for 30 days in 1, 6 and 12 months
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- 1 month:
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Intervention group = 28.8%
-
Control group = 23.4%
-
OR 1.56 (1.05–2.33)
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- 6 months: Intervention group = 28.8%
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Control group = 23.4%
-
OR 1.47 (0.91–2.39)
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- 12 months:
-
Intervention group = 13.0%
-
Control group = 12.2%
-
OR 1.21 (0.72–2.03)
|
Busch et al. 2017 |
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USA
-
Pilot Unicentric
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Out. 2013 Apr. 2015
|
|
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Single group (n = 28)
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• Five counseling sessions in weeks 1, 3, 6, 9 and 12 post discharge. Up to 4 additional contacts according to need
|
|
-
Abstinence in the last 7 days, confirmed by monoxymetry, assessed at the 12th and 24th weeks after discharge.
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Result
-
There was no difference between the intervention groups and the control group
-
• 12th week:
-
• Intervention group = 48.0%
-
• Control group = 44.8%
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• 24th week:
-
• Intervention group = 45.8%
-
• Control group = 42.3%
|
Cruvinel 2016 |
-
Brasil Pilot
-
Unicentric
-
Jun. 2015 Mar. 2016
|
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66 patients
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Hospitalized smokers
|
|
|
-
Self-reported abstinence in the last 7 days, 30 days after discharge and 90 days after discharge Abstinence confirmed by monoxymetry 90 days after discharge
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Result
-
There was no difference between the groups in the 1st and 3rd outcomes and there was a difference in the 2nd outcome
-
• 30 days after discharge:
-
- Intervention group = 25.0% abstinence
-
- Control group = 9.1%
-
- (p = 0.13)
-
• 90 days after discharge:
-
- Intervention group = 31.8%
-
- Control group = 9.1%
-
- (p = 0.04)
-
• Abstinence confirmed by monoxymetry:
-
- Intervention group = 20.5%
-
- Control group = 4.5%
-
- (p = 0.09)
|