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Preoperative factors for the development of acute kidney injury after cardiac surgery: prospective study

OBJECTIVES: To evaluate the clinical characteristics and co-morbidities associated with development of Acute kidney injury (AKI) after cardiac surgery in patients of a predominantly tertiary care university hospital. METHODS: One hundred and fifty cardiac surgery patients were prospectively studied at the Botucatu School of Medicine University Hospital - UNESP, using a protocol which started 48h before and finished 48h after surgery. AKI was defined as a 30% increase in baseline serum creatinine. RESULTS: Were expressed as mean ± standard deviation or median, with a significance level of 5%. Results: There was a slight male predominance (57%); mean age of the studied population was 56±14 years. Sixty-five per cent of patients underwent myocardial revascularization. AKI was diagnosed in 34% of cases. Multivariate analysis showed that age over 60 years and peripheral vascular disease were significantly associated with AKI development. CONCLUSION: AKI was a common complication in cardiac surgery patients at this hospital. AKI was associated with age over 60 years and presence of peripheral vascular disease.

Acute kidney injury; Acute renal failure; Cardiac surgery; Complications


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