Giant cell reparative granuloma is an uncommon bone lesion accounting for slightly less than 7% of all benign tumors of the jaw and affecting predominantly females. It probably represents a reparative reaction to a traumatic injury, although history of trauma is not always confirmed. The characteristic radiological feature is a uni- or multilocular lytic bone defect eroding the bone cortical and occasionally presenting with calcifications within the lesion. We report the most important clinical and radiological features observed in five patients with giant cell reparative granuloma involving the mandible and the maxillae and discuss the main aspects for the differential diagnosis with other fibro-osseous lesions that affect the facial bones.
Giant cell reparative granuloma; Computed tomography; Mandible; Maxilla; Neoplasm