Comparison of standardized uptake values measured on <sup>18</sup>F-NaF PET/CT scans using three different tube current intensities

Valadares, Agnes Araujo; Duarte, Paulo Schiavom; Woellner, Eduardo Bechtloff; Coura-Filho, George Barberio; Sapienza, Marcelo Tatit; Buchpiguel, Carlos Alberto

doi:10.1590/0100-3984.2014.0034

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ORIGINAL ARTICLES • Radiol Bras 48 (1) • Jan-Feb 2015 • https://doi.org/10.1590/0100-3984.2014.0034 copy

Comparison of standardized uptake values measured on ¹⁸F-NaF PET/CT scans using three different tube current intensities^* * Study developed at Unit of Nuclear Medicine - Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira (Icesp), São Paulo, SP, Brazil.

Authorship SCIMAGO INSTITUTIONS RANKINGS

Objective:

To analyze standardized uptake values (SUVs) using three different tube current intensities for attenuation correction on ¹⁸FNaF PET/CT scans.

Materials and Methods:

A total of 254 ¹⁸F-NaF PET/CT studies were analyzed using 10, 20 and 30 mAs. The SUVs were calculated in volumes of interest (VOIs) drawn on three skeletal regions, namely, right proximal humeral diaphysis (RH), right proximal femoral diaphysis (RF), and first lumbar vertebra (LV1) in a total of 712 VOIs. The analyses covered 675 regions classified as normal (236 RH, 232 RF, and 207 LV1).

Results:

Mean SUV for each skeletal region was 3.8, 5.4 and 14.4 for RH, RF, and LV1, respectively. As the studies were grouped according to mAs value, the mean SUV values were 3.8, 3.9 and 3.7 for 10, 20 and 30 mAs, respectively, in the RH region; 5.4, 5.5 and 5.4 for 10, 20 and 30 mAs, respectively, in the RF region; 13.8, 14.9 and 14.5 for 10, 20 and 30 mAs, respectively, in the LV1 region.

Conclusion:

The three tube current values yielded similar results for SUV calculation.

¹⁸F-NaF PET/CT; SUV; Tube current; mAs

	n	Weight (mean ± SD)	Height (mean ± SD)	Body mass index (mean ± SD)	Age (mean ± SD)	Sex (% female)
Total	254	69 ± 15	159 ± 8	27 ± 6	60 ± 14	66
10 mAs	73	68 ± 14	160 ± 9	27 ± 5	60 ± 12	62
20 mAs	83	70 ± 16	158 ± 8	28 ± 7	59 ± 15	67
30 mAs	98	67 ± 15	159 ± 8	27 ± 6	60 ± 14	67
p value		0.44	0.59	0.21	0.78	0.68

	RH		RF		LV1
	Mean ± SD SUV	n	Mean ± SD SUV	n	Mean ± SD SUV	n
Total	3.8 ± 1.4	236	5.4 ± 2.1	232	14.4 ± 3.7	207
10 mAs	3.9 ± 1.3	67	5.4 ± 1.6	64	13.8 ± 3.3	60
20 mAs	3.9 ± 1.5	79	5.5 ± 2.0	79	14.9 ± 4.3	66
30 mAs	3.7 ± 1.4	90	5.4 ± 2.3	89	14.5 ± 3.5	81
p value	0.80		0.88		0.21

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[1] Mailing Address: Dra. Agnes Araujo Valadares. Avenida Doutor Arnaldo, 251, 4º Subsolo (Medicina Nuclear), Cerqueira César. São Paulo, SP, Brazil, 01246-000. E-mail: agnesvaladares@me.com

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Comparison of standardized uptake values measured on 18F-NaF PET/CT scans using three different tube current intensities* * Study developed at Unit of Nuclear Medicine - Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira (Icesp), São Paulo, SP, Brazil.

Objective:

Materials and Methods:

Results:

Conclusion:

Comparison of standardized uptake values measured on ¹⁸F-NaF PET/CT scans using three different tube current intensities^* * Study developed at Unit of Nuclear Medicine - Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira (Icesp), São Paulo, SP, Brazil.