Purpose: To investigate the association of overweight and abdominal fat with CRC/Ad. Methods: From January 2007 to December 2008, 1287 patients over 50 years of age, without known risk factors for CRC/Ad (455 men and 832 women), were submitted to a complete colonoscopy and had the BMI and WHR calculated. Student t-test was used for statistical analysis of means and chi-square to compare absolute numbers. A significant P-value was defined as < 0,05. Results: Neoplastic lesions were found in 542 (42,1%) subjects, being 231 (50,7%) male and 311 (37,3%) female. BMI > 30 led to 43 (18,6%) CRC/Ad male and 84 (27%) female P> 0,05 Patients with BMI < 30 were found to have CRC/Ad 188 (49,4%) male and 227 (36%) female P> 0,05. WHR was 0,96±0,05 cm for male with tumor and 0,94±0,07 without tumor P< 0,01. For female WHR was 0,89±0,06 with tumor and 0,88±0,06 without tumor P< 0,05. Conclusions: These findings suggests that BMI was not associated with CRC/Ad but WHR could be a predictor for an increased risk of colon neoplasia.
Colon Cancer; Colon Adenoma; Obesity; BMI; Risk factors
