The Cardiac Surgery Service of Campo Grande, Santa Casa/MS performed on September 23 rd, 1994 an orthotopic cardiac transplantation in a 27 year-old man with idiopathic dilated cardiomyopathy, which elapsed without abnormalities. The patient left the ICU in 7 days and was discharged at 40 th postoperative day, receiving cyclosporine, azathioprine and prednisone for graft support; captopril, furosemide and aspirin. Presented at one year follow-up, 2 rejection episodes, mil and moderate, when the immunesupressivet herapy dose was modified. On September 1995, at follow up, an obstructive lesion about 50% in the right coronary artery was detected on coronary angiography. We decided to change therapy; diltiazen substituted for captopril was associated with vitamin complex (betacarotene, C and E) plus selenium, in attempt to avoid obstructive lesion progression. Dietetic guidance by nutritionist was also performed. After twelve months on the new therapy, coronary angiography demonstrated a significative reduction of the obstructive lesion in the right coronary artery. At follow up the patient has presented normal level of serum lipids.Presently, the patient is on his third year follow up, asymptomatic and has performed is habitual work, without problems.
Heart transplantation; Cardiomyopathy; Coronary vessels; Coronary disease; Heart transplantation; Heart transplantation; Antioxidants
