INTRODUCTION: Performing diagnostic cardiac catheterization and percutaneous coronary intervention (PCI) in the same procedure (ad hoc PCI) has been an increasing practice. Studies have indicated a reduction in hospital costs, greater patient commodity and less vascular complications as advantages of this strategy. METHODS: Six hundred and fifty-one patients with stable angina were randomized to ad hoc PCI or staged PCI. Primary endpoint was the composition of cardiac death, acute myocardial infarction (AMI), urgent cardiac surgery, stroke, or hemorrhagic complications. RESULTS: Primary endpoint was observed in 2.9% for ad hoc PCI versus 4.4% for staged PCI (P = 0.406). Analysis of isolated clinical events did not find significant differences between groups: death from cardiac cause was observed in 1% for ad hoc PCI versus 0.3% for staged PCI (P = 0.354); AMI in 1.3% for ad hoc PCI versus 1.2% for staged PCI (P > 0.99), and stroke in 0.3% for ad hoc PCI versus 0.3% for staged PCI (P > 0.99). The rate of hemorrhagic complications was significantly greater for staged PCI (3.5% versus 1%; P = 0.035). Independent predictors of primary endpoint were: previous myocardial infarction (OR = 6.287; CI 95% 1.62-24.36; P = 0.008), peripheral vascular disease (OR = 16.97; CI 95% 6.3945.01; P = 0.0001), and multiple coronary artery disease (OR = 13.97; CI 95% 3.65-53.50; P = 0.0001). CONCLUSION: The study showed that ad hoc PCI is as safe and efficient as staged PCI in patients with stable angina, and it is associated to a significantly lower rate of hemorrhagic complications related to vascular access.
Angioplasty, transluminal, percutaneous coronary; Stents; Coronary disease; Angina pectoris; Time factors
