Incidence, mortality and survival of prostate cancer in two municipalities with a high human development index in Mato Grosso, Brazil

Evangelista, Flávio de Macêdo; Melanda, Francine Nesello; Modesto, Viviane Cardozo; Soares, Mariana Rosa; Neves, Marco Aurélio Bertúlio das; Souza, Bárbara da Silva Nalin de; Sousa, Neuciani Ferreira da Silva e; Galvão, Noemi Dreyer; Andrade, Amanda Cristina de Souza

doi:10.1590/1980-549720220016.supl.1

Acessibilidade / Reportar erro

Brasil

Revista Brasileira de Epidemiologia

Español English

Brasil

Español English

sumário « anterior atual seguinte »

Sumário

Original Article • Rev. bras. Epidemiol. 25 (Supl 1) • 2022 • https://doi.org/10.1590/1980-549720220016.supl.1 copy

Incidence, mortality and survival of prostate cancer in two municipalities with a high human development index in Mato Grosso, Brazil

Authorship SCIMAGO INSTITUTIONS RANKINGS

ABSTRACT:

Objective:

To analyze the incidence, mortality and survival of prostate cancer in Cuiabá and Várzea Grande, Brazil from 2000 to 2016.

Methods:

Data from the Population-based Cancer Registry and the Mortality Information System were used. Mortality and incidence trends were analyzed using joinpoint regression models by age group. Survival analyses were performed using the Kaplan-Meier method, and hazard ratio was estimated by age group.

Results:

From 2000 to 2016, 3,671 new cases and 892 deaths for prostate cancer were recorded. The average incidence and mortality rates were 87.96 and 20.22 per 100,000, respectively. Decreasing incidence trend was noted for all age groups from 2006 to 2016 (APC=-3.2%) and for men with 80+ years of age from 2000 to 2016 (APC=-3.0%), and increasing mortality trend for men 60-69 years of age from 2000 to 2009 (APC=3.2%). The specific five-year survival rate for prostate cancer was 79.6% (95%CI 77.2–81.9), and the rate decreased with advanced age (HR=2.43, 95%CI 1.5–3.9, for those 70 to 79 years old and HR=7.20, 95%CI 4.5–11.5, for those 80 or older).

Conclusion:

The incidence rate of prostate cancer showed a decreasing trend from 2006 for all age groups; the mortality rate was stable in that period, and worse prognosis was observed in men 70 years or older.

Keywords:
Prostate cancer; Incidence; Mortality; Survival

Trend		Year	APC	95%CI	AAPC	95%CI
Incidence
Age group
	50 to 59 years	2000–2016	2.2	(-1.6–6.2)	2.2	(-1.6–6.2)
	60 to 69 years	2000–2016	-0.5	(-2.5–1.5)	-0.5	(-2.5–1.5)
	70 to 79 years	2000–2016	-2.1	(-4.1–0.0)	-2.1	(-4.1–0.0)
	80 years or older	2000–2016	-3.0^* * (p < 0.05).	(-5.7–-0.3)	-3.0^* * (p < 0.05).	(-5.7–-0.3)
	All ages	2000–2006	5.4	(-2.2–13.5)	-0.1	(-3.1–3.0)
	All ages	2006–2016	-3.2^* * (p < 0.05).	(-6.1–-0.3)	-0.1	(-3.1–3.0)
Mortality
Age group
	50 to 59 years	2000–2016	0.7	(-6.6–8.5)	0.7	(-6.6–8.5)
	60 to 69 years	2000–2009	3.2^* * (p < 0.05).	(0.2–6.2)	-0.2	(-2.7–2.2)
	60 to 69 years	2009–2016	-4.5	(-9.1–0.4)	-0.2	(-2.7–2.2)
	70 to 79 years	2000–2007	5.8	(-0.7–12.6)	1.8	(-6.9–11.2)
		2007–2010	-17.0	(-49.8–36.9)
		2010–2016	7.8	(-0.7–16.9)
	80 years or older	2000–2016	3.9	(-0.6–8.6)
	All ages	2000–2016	1.0	(-0.8–2.7)	1.0	(-0.8–2.7)

	New cases		Deaths		Survival - 60 months	HR (95%CI)
	n	%	n	%	(95%CI)	HR (95%CI)
Age group
<50 years	28	2.4	1	3.6	96.3 (76.5–99.5)	-
50 to 59 years	219	18.6	23	10.5	89.4 (84.5–92.8)	1.00
60 to 69 years	447	38.0	63	14.1	85.5 (81.8–88.5)	1.39 (0.9–2.2)
70 to 79 years	334	28.4	74	22.2	75.6 (70.3–80.1)	2.43 (1.5–3.9)^* * (p < 0.05).
80 years or older	148	12.6	73	49.3	46.0 (37.2–54.4)	7.20 (4.5–11.5)^* * (p < 0.05).
All ages	1,203	28.4	234	19.4	79.6 (77.2–81.9)

Associação Brasileira de Saúde Coletiva Av. Dr. Arnaldo, 715 - 2º andar - sl. 3 - Cerqueira César, 01246-904 São Paulo SP Brasil , Tel./FAX: +55 11 3085-5411 - São Paulo - SP - Brazil
E-mail: revbrepi@usp.br

Acompanhe os números deste periódico no seu leitor de RSS

[1] Corresponding author: Flávio de Macêdo Evangelista. Rua 32 Quadra 54 Casa 27, CPA III Setor V, CEP: 78058-378, Cuiabá (MT), Brazil. E-mail: flavio.ufmt.isc@gmail.com