Acetic acid-induced abdominal writhing, croton oilinduced mice ear oedema test and carrageenan-induced peritonitis were used to study the analgesic and antiinflammatory activities of the aqueous fraction of the ethanolic extract from Spiranthera odoratissima leaves. It caused a dose dependent inhibition of acetic acid-induced abdominal writhing, reduction in ear oedema formation and leukocyte migration. The results suggest that Spiranthera odoratissima leaves contain compounds with antiinflammatory activity.