Effect of defatted sesame (Sesamum indicum L.) flour on the blood glucose level in type 2 diabetic women

There is an increment in the researches on plants and whole grains with hypoglycemic activity in order to prevent and treat Diabetes Mellitus which has increased rapidly on serious proportions all over the world. This study aimed at evaluating the effect of defatted Sesamum indicum L. flour on blood glucose level in type 2 diabetic women on diet therapy. A controlled and open-label clinical trial, with two groups, experimental group (GE) and control group (GC) were evaluated at the basal line (AB), at thirty day (A-30) and sixty day (A-60). The general characteristics in both groups were similar. There was a significant difference at fasting glucose level (GJ) (p = 0.004) on AB, GJ (p = 0.002) and weight (p = 0.020) on A-30, and only weight (p = 0.011) on A-60. There was no significant difference at postprandial glucose level (GP) and glycosylated hemoglobin level at all the evaluation between the groups. There was a significant difference between AB - A-30 of weight in two groups, and AB - A-60 of GP (p = 0.04) and weight (p = 0.01) on GE, but only of weight (p = 0.03) on GC. The defatted sesame contributed to the glycemic control and weight in diabetic women in a cheap, tasty and healthy manner.

Sesamum indicum; Pedaliaceae; flour, diabetes; hypoglycemic activity; medicinal plants; natural products; nutraceutic