The species Dioclea grandifloraMart. ex. Benth., Fabaceae is a plant that belongs to the Fabaceae family, popularly known as "mucunã-de-caroço" and "olho-de-boi". It can be found distributed in mountainous regions and in the scrub savanna of Brazil. The aqueous, ethanol and hydroalcoholic extracts of stem bark, root bark and leaves of D. grandifloraon concentration from 313 µg/mL to 10.000 µg/mL, were analyzed by the agar diffusion technique, front to twenty microorganisms, representatives of Gram-positive and Gram-negative bacteria, filamentous fungi and yeasts. The aqueous extract of stem bark, on concentration of 10.000 µg/mL, inhibited the growth of Staphylococcus aureuswith a 20 mm halo. Hydroalcoholic extract of stem bark only inhibited S. aureuswith a halo of 18 mm, while leaves extract inhibited the growth of two dermatophytes, Trichophyton mentagrophytes and Microsporum canis. On the other hand, hydroalcoholic extract of root bark only inhibited M. caniswith a halo of 15 mm diameter. From the fractions of aqueous extract of leaves, only ethyl acetate inhibited the growth of Streptococcus epidermides, Candida albicans, T. mentagrophytese M. canis. For the ethanol extract of stem bark, the aqueous fraction inhibited S. epidermides and S. aureus.
Dioclea grandiflora; Fabaceae; antimicrobial activity; natural products
