This paper presents a review of the main microbiological quality standards of non-sterile oral pharmaceuticals, plant raw materials and phytotherapics, in a cronological and comparative discussion. This critical study aims at verifying the adaptability of existing standards to the actual production conditions of phythotherapics, related to its nature. The authors suggest microbial limits for such a products as a way to achieve a desirable quality to guaranfee safety, efficiency and integrity of the end product.
Microbiological standards; Oral non-sterile pharmaceuticals; Phytotherapics; Plant drugs