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Paniculatumoside G, a new C21 steroidal glycoside from Cynanchum paniculatum

ABSTRACT

A new C21 steroidal glycoside, paniculatumoside G, together with neocynapanogenin C isolated for the first time from the natural source and two known compounds were isolated and characterized from the roots and rhizomes of Cynanchum paniculatum (Bunge) Kitag. ex H.Hara, Apocynaceae, a commonly used Traditional Chinese Medicine. On the basis of spectroscopic analysis, including HR-ESI-MS, 1D and 2D NMR spectral data, the structure of the new C21 steroidal glycoside was elucidated as neocynapanogenin H 3-O-β-D-oleandropyranoside.

Keywords:
Asclepiadaceae; Cynanchum paniculatum; C21 steroidal glycoside; Neocynapanogenin H 3-O-β-D-oleandropyranoside

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