Medication safety of older patients in the hospital setting: a scoping review

A scoping review was conducted on medication safety among older patients in the hospital setting involving searches of the LILACS, SCIELO, MEDLINE, and PUBMED databases Health descriptors were used according to DECS: patient safety, elderly, medications, hospital. The study included complete articles available in full, in Portuguese, English or Spanish. Duplicate articles, theses and dissertations were excluded.

Results

The search retrieved 172 publications. After reading of titles and abstracts, 8 articles that met the inclusion criteria were selected. The final sample of this scoping review comprised 8 selected studies, while the rest were excluded for being off-topic. The review allowed mapping of a significant number of publications on medication safety for hospitalized older adults.

Conclusion

This review found proposed strategies for preventing medication errors in the hospital environment.

Keywords
Patient Safety; Nursing; Aged; Pharmacological Treatment; Hospital

Identification	Author	Study design	Objective	Country	Quality of evidence**
A1	Martins et al.¹¹11 Martins ACM, Giordani F, Gonçalves M de C, Guaraldo L, Rozenfeld S. Óbitos por eventos adversos a medicamentos no Brasil: Sistema de Informação sobre Mortalidade como fonte de informação. Cad Saúde Pública. 23 de setembro de 2022;38:e00291221.,	Ecological study	To identify Adverse Drug Events (ADE) registered on the SIM, estimating rate and analyzing distribution by year, age group and event type.	Brazil	Level 4
A2	Santos et al.¹²12 Santos KFS, Silva CML, Barros IM da C, Silva LM. Potenciais interações medicamentosas em pacientes idosos da clínica médica de um hospital universitário. Sci Plena [Internet]. 12 de julho de 2022 [citado 9 de maio de 2024];18(6). Disponível em: https://www.scientiaplena.org.br/sp/article/view/6288,	Cross-sectional study	To asses potential drug-drug interactions in patients from a clinic at a university hospital	Brazil	Level 4
A3	Meireles et al.¹³13 Meireles IB, Pessanha CM, Ramos AC de A, Silva RCL da, Silva AS da, Silva RFA da. Fall among hospitalized patients and the use of drugs that increase the risk / Queda entre pacientes hospitalizados e o uso de medicamentos que potencializam o risco. Rev Pesqui Cuid É Fundam Online. 26 de outubro de 2021;13:1671–7.,	Cross-sectional study	To estimate the prevalence rate of falls in the study setting.	Brazil	Level 4
A4	Moraes et al.¹⁴14 Moraes JT, Maia JM, Trindade OM, Oliveira LA, Sanches C, Trevisan DD. Fatores associados para potenciais interações medicamentosas clinicamente significantes em terapia intensiva adulto. Med Ribeirão Preto. 11 de dezembro de 2020;53(4):379–88.,	Cross-sectional study	To characterize the major potential interactions of drugs contraindicated in adult intensive care and determine their prevalence, medications and factors associated with exposure of these interactions.	Brazil	Level 4
A5	Eshetie et al.¹⁵15 Eshetie TC, Marcum ZA, Schmader KE, Gray SL. Medication use quality and safety in older adults: 2020 update. J Am Geriatr Soc. fevereiro de 2022;70(2):389–97.,	Randomized study	To identify 4 example articles focusing on medication use quality and safety in 2020.	USA	Level 1
A6	Karapinar Çarkit et al.¹⁶16 Karapinar-Çarkit F, Van Den Bemt PMLA, Sadik M, Van Soest B, Knol W, Van Hunsel F, et al. Opportunities for changes in the drug product design to enhance medication safety in older people: Evaluation of a national public portal for medication incidents. Br J Clin Pharmacol. outubro de 2020;86(10):1946–57.,	Observational study	To assess the medication-related problems/errors reported to the Dutch medication incident registry and disseminated for information to pharmacists.	Holland	Level 4
A7	Leite et al.¹⁷17 Leite KRL, Ribeiro VF, Carvalho JSM. Ferramentas tecnológicas para prevenção dos erros de medicação no ambiente hospitalar. An Semin Tecnol Apl Educ E Saúde [Internet]. 2019 [citado 9 de maio de 2024]; Disponível em: https://revistas.uneb.br/index.php/staes/article/view/8225,	Review	Determine the main health technologies used as tools for preventing medication errors in the hospital setting	Brazil	Level 5
A8	Costa et al.¹⁸18 Costa JMD, Martins JM, Pedroso LA, Reis AMM. Pharmacotherapeutic monitoring in a multi-residence program: contributions to the safety of hospitalized elderly. Rev Bras Farm Hosp Serv Saude [Internet]. 2019;5(2) [Acesso em 09 . 2024]. Disponível em: https://www.rbfhss.org.br/sbrafh/article/view/196,	Cross-sectional study	To describe the contributions of activities of resident pharmacists, under a multiprofessional program, to the safety of hospitalized older adults.	Brazil	Level 4

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[1] Correspondence Adrya Thayanne Henriques da Silva adryathayanne45@gmail.com

Brasil

Brasil

Medication safety of older patients in the hospital setting: a scoping review

Abstract

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Method

Results

Conclusion

Objective