1
|
Xiong et al. (2020)1212 Xiong X, Wei H, Zhang Z, et al. Vaginal delivery report of a healthy neonate born to a convalescent mother with COVID–19. J Med Virol. 2020;92(09):1657–1659. Doi: 10.1002/jmv.25857 https://doi.org/10.1002/jmv.25857...
; China |
1 |
RT-PCR |
(25) |
2nd (26 GW) |
38°C fever, dry cough, and tremor |
Radiological: pulmonary opacity
Laboratory: neutrophilia and lymphocytopenia
|
Without repercussions |
2
|
Li et al. (2020)1515 Li N, Han L, Peng M, et al. Maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia: a case-control study. Clin Infect Dis. 2020;71(16):2035–2041. Doi: 10.1093/cid/ciaa352 https://doi.org/10.1093/cid/ciaa352...
; China |
16 |
RT-PCR |
(31,5)26–37 |
3rd (35 GW) |
Fever (4;25.0%) |
Radiological: bilateral pneumonia 43.75% (7) and unilateral pneumonia 50% (8)
Laboratory: leukopenia and neutrophilia
|
14 (87.5%) Cesarean deliveries
3 (18.75%) Premature births, of which: 2 (66.67%) premature rupture of ovarian membranes (RPMO) and 1 (33.3%) bleeding
2 (12.5%) fetal distress
|
3
|
Chen et al. (2020)2727 Chen S, Liao E, Cao D, Gao Y, Sun G, Shao Y. Clinical analysis of pregnant women with 2019 novel coronavirus pneumonia. J Med Virol. 2020;92(09):1556–1561. Doi: 10.1002/jmv.25789 https://doi.org/10.1002/jmv.25789...
; China |
5 |
RT-PCR |
(28) 25–31 |
3rd (39 GW) |
Fever (after delivery) and dry cough (2;40.0%) |
Radiological: bilateral pneumonia 60% (3) and 40% (2) unilateral
Laboratory: increased CRP (4; 80.0%) and alkaline phosphates (4; 80.0%); leukopenia 40% (2)
|
2 (40.0%) Cesarean deliveries |
4
|
Yu et al. (2020)1313 Yu N, Li W, Kang Q, et al. Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study. Lancet Infect Dis. 2020;20(05):559–564. Doi: 10.1016/S1473-3099(20)30176-6 https://doi.org/10.1016/S1473-3099(20)30...
; China |
7 |
RT-PCR |
(32) 29–34 |
3rd (39 GW) |
Fever (86%;6), cough, dyspnea, and diarrhea (14%;1,each) |
Radiological: 86% (6) bilateral pneumonia and 14% (1) unilateral
Laboratory: neutrophilia (71%; 5), lymphopenia (71%; 5), thrombocytopenia (29%; 2) and elevation of D-dimer (100%; 7), alanine aminotransferase (29%; 2) and CRP (100%; 7)
|
Infected NB 36h after delivery |
5
|
Kang et al. (2020)1616 Kang X, Zhang R, He H, et al. [Anesthesia management in cesarean section for a patient with coronavirus disease 2019]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2020;49(01):249–252; China |
1 |
RT-PCR |
30 |
3rd (35 GW). |
Cough |
Radiological: pneumonia and bilateral pleural effusion
Laboratory: Without changes
|
Emergency cesarean delivery
Fetal bradycardia
|
6
|
Liu et al. (2020)4545 Liu D, Li L, Wu X, et al. Pregnancy and perinatal outcomes of women with coronavirus disease (COVID-19) pneumonia: a preliminary analysis. AJR Am J Roentgenol. 2020;215(01): 127–132. Doi: 10.2214/AJR.20.23072 https://doi.org/10.2214/AJR.20.23072...
; China |
15 |
RT-PCR |
32 (23–40) |
1st to 3rd (12 to 38 GW). |
Fever (86.6%; 13); Cough (60.0%; 9); fatigue (26.7%; 4); myalgia (20.0%; 3); dyspnea, odynophagia, and diarrhea (6.6%; 1, each) |
Radiological: ground-glass opacity and late pulmonary consolidations
Laboratory: lymphocytopenia (80.0%; 12) and increased value of C-reactive protein (66.6%; 10)
|
10 (66.6%) cesarean deliveries
3 (20.0%) premature births
|
7
|
Chen et al. (2020)1414 Chen H, Guo J, Wang C, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020;395(10226):809–815. Doi: 10.1016/S0140-6736(20)30360-3 https://doi.org/10.1016/S0140-6736(20)30...
; China |
9 |
RT-PCR |
30 (26–40) |
3rd (37 GW) |
Fever (77.7%; 7); Cough (44.4%; 4); myalgia (33.3%; 3); odynophagia and malaise (22.2%; 2, each) |
Radiological: ground-glass opacity (88.8%; 8)
Laboratory: lymphocytopenia (55.5%; 5), elevation of aminotransferases (33.3%; 3) and C-reactive protein-PCR (66.6%; 6)
|
9 (100.0%) cesarean deliveries
4 (44.4%) newborns had birth weight less than 2500 g
1 (11.1%) PROM
|
8
|
Liu et al. (2020)1717 Liu Y, Chen H, Tang K, Guo Y.Withdrawn: Clinical manifestations and outcome of SARS-CoV-2 infection during pregnancy. J Infect. 2020;•••:S0163-4453(20)30109-2. Doi: 10.1016/j.jinf.2020.02.028 [ahead of print] https://doi.org/10.1016/j.jinf.2020.02.0...
; China |
13 |
RT-PCR |
29 (22–36) |
2 patients in the 2nd (26 GW); 11 patients in the 3rd (35 GW) |
Fever and fatigue (10; 77%); Dyspnea (3; 23%) |
NR |
10 (77%) cesarean deliveries, 5 (38.4%) of which were emergency
6 (46%) premature birth
3 (23%) fetal distress.
1 (7.6%) PROM
1 (7.6%) stillborn
1 (7.6%) maternal multiple organ dysfunction syndrome (MODS)
|
9
|
Li et al. (2020)1818 Li Y, Zhao R, Zheng S, et al. Lack of vertical transmission of severe acute respiratory syndrome coronavirus 2, China. Emerg Infect Dis. 2020;26(06):1335–1336. Doi: 10.3201/eid2606.200287 https://doi.org/10.3201/eid2606.200287...
; China |
1 |
RT-PCR |
30 |
3rd (35 GW) |
Dry cough, fever, and dyspnea |
Radiological: bilateral irregular pulmonary infiltrates
Laboratory: slightly abnormal.
|
Emergency cesarean delivery
Fetal bradycardia
|
10
|
Chen et al. (2020)1919 Chen S, Huang B, Luo DJ, et al. [Pregnancy with new coronavirus infection: clinical characteristics and placental pathological analysis of three cases]. Zhonghua Bing Li Xue Za Zhi. 2020;49(05): 418–423. Doi: 10.3760/cma.j.cn112151-20200225-00138 https://doi.org/10.3760/cma.j.cn112151-2...
; China |
3 |
RT-PCR |
29,6 (23–34) |
3rd (36.6 GW) |
Pre or postnatal fever (100%, 3) and chest pain (33.3%; 1). |
Radiological: bilateral ground-glass opacities and bronchiectasis (100%, 3)
Laboratory: significant increase in CRP (100%, 3)
|
3 (100.0%) cesarean deliveries
1 (33.3%) premature birth
1 (33.3%) premature placental displacement
1 (33.3%) placenta previa
1 (33.3%) NB with LBW
|
11
|
Zhang et al. (2020)2020 Zhang L, Jiang Y, WeiM, et al. [Analysis of the pregnancy outcomes in pregnant women with COVID-19 in Hubei Province]. Zhonghua Fu Chan Ke Za Zhi. 2020;55(03):166–171; China |
16 |
RT-PCR |
29 (24–34) |
3rd (38 GW) |
Cough; Chest pain; dyspnea, and diarrhea |
NR |
16 (100%) emergency cesarean section
3 (18.7%) premature births
2 (12.5%) fetal distress
3 (18.7%) rupture of membranes
1 (6.25%) fetal distress and fetal bradycardia
1 (6.25%) severe maternal pneumonia
|
12
|
Yan et al. (2020)2121 Yan J, Guo J, Fan C, et al. Coronavirus disease 2019 in pregnant women: a report based on 116 cases. Am J Obstet Gynecol. 2020; 223(01):111.e1–111.e14. Doi: 10.1016/j.ajog.2020.04.014 https://doi.org/10.1016/j.ajog.2020.04.0...
; China |
116 |
RT-PCR |
31 (24-41) |
3rd (38 GW)
1st (4;3.4%)
2nd (6;5.2%)
3rd (96;91.4%)
|
27 (23.3%) asymptomatic Fever (50.9%; 59), cough (28.4%; 33), fatigue (12.9%; 15), dyspnea (7.8%; 9); odynophagia (8.6%; 10); myalgia (5.3%; 6); diarrhea (0.9%; 1) |
Radiological: bilateral ground-glass pneumonia (96.3%; 104)
Laboratory: lymphopenia and increased CRP (44.0%; 51), leukopenia (24.1%; 28)
|
99 deliveries, 85 (85.9%) of which were cesarean and 33 (38.8) indications due to COVID-19 21 (21.2%) premature births
6 (6.0%) PROM
1 abortion
1 neonatal death from asphyxiation.
8 (6.9%) severe pneumonia with ventilatory support
|
13
|
Ferrazzi et al. (2020)2222 Ferrazzi EM, Frigerio L, Cetin I, et al. COVID-19 Obstetrics Task Force, Lombardy, Italy: Executive management summary and short report of outcome. Int J Gynaecol Obstet. 2020;149(03): 377–378. Doi: 10.1002/ijgo.13162 https://doi.org/10.1002/ijgo.13162...
; Itália |
42 |
RT-PCR |
NR |
NR |
Dyspnea (20; 48%) |
Radiological: interstitial pneumonia (20; 48.0%)
Laboratory: NR
|
18 (43%) cesarean deliveries
2 (4.7%) premature births
7 (35%) severe pneumonia with ventilatory support
|
14
|
Kalafat et al. (2020)2323 Kalafat E, Yaprak E, Cinar G, et al. Lung ultrasound and computed tomographic findings in pregnant woman with COVID-19. Ultrasound Obstet Gynecol. 2020;55(06):835–837. Doi: 10.1002/uog.22034 https://doi.org/10.1002/uog.22034...
; Turquia |
1 |
RT-PCR |
32 |
3rd (35 GW and 3 days) |
Cough (1; 100%), dyspnea (1; 100%) |
Radiological: bilaterally thick pulmonary B lines, located in the posterior basal segments of the lung
Laboratory: NR
|
Premature cesarean delivery
Reduced fetal movements
|
15
|
Wen et al. (2020)2424 Wen R, Sun Y, Xing QS. A patient with SARS-CoV-2 infection during pregnancy in Qingdao, China. J Microbiol Immunol Infect. 2020;53(03):499–500. Doi: 10.1016/j.jmii.2020.03.004 https://doi.org/10.1016/j.jmii.2020.03.0...
; China |
1 |
RT-PCR |
31 |
3rd (30 GW) |
Diarrhea. (1; 100%) |
Radiological: irregular consolidation and bilateral ground-glass opacities, mainly distributed in the sub-plastic regions. Left pleural effusion
Laboratory: NR
|
Without gestational changes |
16
|
Fan et al. (2020)2525 Fan C, Lei D, Fang C, et al. Perinatal Transmission of 2019 Coronavirus Disease-Associated Severe Acute Respiratory Syndrome Coronavirus 2: Should We Worry? Clin Infect Dis. 2021;72 (05):862–864. Doi: 10.1093/cid/ciaa226 https://doi.org/10.1093/cid/ciaa226...
; China |
2 |
RT-PCR |
31 (29-34) |
3rd (36.5 GW) |
Chills, fever (37.6±38.5°C), nasal congestion and odynophagia |
Radiological: irregular consolidation and bilateral opacities
Laboratory: lymphopenia (1; 50.0%)
|
2 (100%) Emergency cesarean delivery
2 (100%) NB had mild neonatal pneumonia
|
17
|
Pierce-Williams et al. (2020)2626 Pierce-Williams RAM, Burd J, Felder L, et al. Clinical course of severe and critical coronavirus disease 2019 in hospitalized pregnancies: a United States cohort study. Am J Obstet Gynecol MFM. 2020;2(03):100134. Doi: 10.1016/j.ajogmf.2020.100134 https://doi.org/10.1016/j.ajogmf.2020.10...
; EUA |
64 |
RT-PCR |
33 |
3rd (29.9 GW) |
Fever, dyspnea |
Radiological: NR
Laboratory: elevation of ferritin, liver enzymes, CRP, interleukin-6, d-dimer, LDH, creatine phosphokinase (CPK)
|
44 (69.0%) severe pneumonia
20 (31.0%) critical illness
14(22.0%)SARS
24 cesarean deliveries
31 (48.4%) premature births, 15 in critical patients
19 (30.0%) invasive mechanical ventilation
1 cardiorespiratory arrest, without maternal mortality
3 (9.0%) postpartum hemorrhage
1 neonatal COVID-19 infection
|
18
|
Blauvelt et al.(2020)2828 Blauvelt CA, Chiu C, Donovan AL, et al. Acute respiratory distress syndrome in a preterm pregnant patient with Coronavirus Disease 2019 (COVID-19). Obstet Gynecol. 2020;136(01):46–51. Doi: 10.1097/AOG.0000000000003949 https://doi.org/10.1097/AOG.000000000000...
; EUA |
01 |
RT-PCR |
34 |
3rd (28 GW) |
Asthenia, fever, myalgia, cough, and dyspnea |
Radiological: bilateral opacities in the lower lobes
Laboratory: lymphopenia and lactate elevation, D-dimer, and CRP
|
Cesarean and premature delivery SARS, with the need to undergo invasive mechanical ventilation
NB with respiratory distress
|
19
|
Hong et al. (2020)2929 Hong L, Smith N, Keerthy M, et al. Severe COVID-19 infection in pregnancy requiring intubation without preterm delivery: A case report. Case Rep Womens Health. 2020;27:e00217. Doi: 10.1016/j.crwh.2020.e00217 https://doi.org/10.1016/j.crwh.2020.e002...
; China |
01 |
RT-PCR e laboratorial |
36 |
2nd (23 weeks) |
Fever, myalgia and dyspnea, cough, tachycardia |
Radiological: opacities in pulmonary bases.
Laboratory: lymphopenia and elevation of transaminases, CPK, and CRP
|
SARS, with the need to undergo invasive mechanical ventilation |
20
|
Li et al. (2020)3030 Li J, Wang Y, Zeng Y, et al. Critically ill pregnant patient with COVID-19 and neonatal death within two hours of birth. Int J Gynaecol Obstet. 2020;150(01):126–128. Doi: 10.1002/ijgo.13189 https://doi.org/10.1002/ijgo.13189...
; China |
01 |
RT-PCR |
31 |
3rd (35 GW) |
Odynophagia, dry cough, fever, and dyspnea |
Radiological: diffuse opacity in bilateral ground glass
Laboratory: lymphopenia, respiratory acidosis and abnormal coagulogram, elevated CRP and interleukin 6
|
Premature cesarean delivery
SARS with multiple organ dysfunction Neonatal death
|
21
|
Schnettler et al. (2020)3131 Schnettler WT, Al Ahwel Y, Suhag A. Severe acute respiratory distress syndromein coronavirusdisease2019-infectedpregnancy: obstetric and intensive care considerations. Am J Obstet Gynecol MFM. 2020;2(03):100120. Doi: 10.1016/j.ajogmf.2020.100120 https://doi.org/10.1016/j.ajogmf.2020.10...
; EUA |
01 |
RT-PCR |
39 |
3rd (31 GW) |
Cough, dyspnea, fever, and asthenia |
Radiological: peripheral diffuse opacities in bilateral ground glass
Laboratory: leukopenia, lymphopenia, thrombocytopenia, elevated transaminases
|
Emergency and premature cesarean delivery. SARS, with the need to undergo invasive mechanical ventilation |
22 |
Wu et al. (2020)3232 Wu C, Yang W, Wu X, et al. Clinical manifestation and laboratory characteristics of SARS-CoV-2 infection in pregnant women. Virol Sin. 2020;35(03):305–310. Doi: 10.1007/s12250-020-00227-0 https://doi.org/10.1007/s12250-020-00227...
; China |
08 |
RT-PCR |
29 |
(26–35) |
3rd (38 GW) |
Fever on admission (1 ;12.5%), and fever in the postpartum period (3; 37.5%) |
Radiological: peripheral diffuse opacities in bilateral ground glass (6; 75.0%)
Laboratory: leukocytosis (6; 75.0%); lymphopenia (5; 62.5%), elevation of D-dimers and creatine kinase (CK) and creatine kinase-MB (CK-MB) in 4 (50.0%) in the postpartum period
|
6 (75.0%) Cesarean delivery
1 fetal distress
|
23 |
Peng et al. (2020)3333 Peng Z, Wang J, Mo Y, et al. Unlikely SARS-CoV-2 vertical transmission from mother to child: A case report. J Infect Public Health. 2020;13(05):818–820. Doi: 10.1016/j.jiph.2020.04.004 https://doi.org/10.1016/j.jiph.2020.04.0...
; China |
01 |
RT-PCR |
25 |
3rd (35 SG) |
Fever, fatigue and dyspnea |
Radiological: peripheral diffuse opacities in bilateral ground-glass pattern
Laboratory: NR
|
Emergency cesarean and premature delivery Fetal distress |
24 |
Breslin et al. (2020)3434 Breslin N, Baptiste C, Gyamfi-Bannerman C, et al. Coronavirus disease 2019 infection among asymptomatic and symptomatic pregnant women: two weeks of confirmed presentations to an affiliated pair of New York City hospitals. Am J Obstet Gynecol MFM. 2020;2(02):100118. Doi: 10.1016/j.ajogmf.2020.100118 https://doi.org/10.1016/j.ajogmf.2020.10...
; EUA |
43 |
RT-PCR |
27 (20–39) |
3rd (37 SG) |
Cough (19; 65.6%); fever (14; 48.3%); myalgia (11; 37.9%). headache (8; 27.6%); dyspnea (7; 24.1%); chest pain (5; 17.2%) |
Radiological: peripheral diffuse opacities in bilateral ground-glass pattern (1; 2.32%)
Laboratory: NR
|
Cesarean delivery (8; 44.4%)
Premature birth (4; 13.8%)
1 PROM
2 (4.6%) severe maternal pneumonia
1 newborn with respiratory distress
|
25 |
Karami et al. (2020)3535 Karami P, Naghavi M, Feyzi A, et al. WITHDRAWN: Mortality of a pregnant patient diagnosed with COVID-19: A case report with clinical, radiological, and histopathological findings. Travel Med Infect Dis. 2020;101665:101665. Doi: 10.1016/j.tmaid.2020.101665 [ahead of print] https://doi.org/10.1016/j.tmaid.2020.101...
; Irã |
01 |
RT-PCR |
27 |
3rd (30 SG) |
Dyspnea, fever, cough, myalgia, and tachypnea |
Radiological: bilateral diffuse peripheral ground-glass opacities and pleural effusion
Laboratory: leukopenia, thrombocytopenia, elevated CRP, lactic dehydrogenase (LDH) Echocardiogram: severe systolic dysfunction right
|
Maternal death from severe acute respiratory syndrome (SARS) and MODS; stillborn |
26 |
Iqba et al. (2020)3636 Iqbal SN, Overcash R, Mokhtari N, et al. An Uncomplicated Delivery in a Patient with Covid-19 in the United States. N Engl J Med. 2020;382(16):e34. Doi: 10.1056/NEJMc2007605 https://doi.org/10.1056/NEJMc2007605...
; EUA |
01 |
RT-PCR |
34 |
3rd (39 GW) |
Fever, cough, chills, and myalgia |
Radiological: diffuse pulmonary opacities
Laboratory: lymphopenia
|
NR |
27 |
Xia et al. (2020)3737 Xia H, Zhao S, Wu Z, Luo H, Zhou C, Chen X. Emergency Caesarean delivery in a patient with confirmed COVID-19 under spinal anaesthesia. Br J Anaesth. 2020;124(05):e216–e218. Doi: 10.1016/j.bja.2020.02.016 https://doi.org/10.1016/j.bja.2020.02.01...
; China |
01 |
RT-PCR |
27 |
3rd (36 GW) |
Fever, cough, drop in oxygen saturation (92%) |
Radiological: bilateral diffuse peripheral ground-glass opacities
Laboratory: neutrophilia, lymphopenia, and elevated CRP
|
Cesarean delivery
Fetal distress
|
28 |
Buonsenso et al. (2020)3838 Buonsenso D, Costa S, Sanguinetti M, et al. Neonatal Late Onset Infection with Severe Acute Respiratory Syndrome Coronavirus 2. Am J Perinatol. 2020;37(08):869–872. Doi: 10.1055/s-0040-1710541 https://doi.org/10.1055/s-0040-1710541...
; Itália |
07 |
RT-PCR |
40 |
3rd (36 GW) |
Cough |
Radiological: diffuse interstitial lung disease
Laboratory: NR
|
2 (28.5%) Cesarean delivery
1 Premature Birth
1 Abortion
2 Neonatal COVID-19 infections
|
29 |
Qiancheng et al. (2020)3939 Qiancheng X, Jian S, Lingling P, et al; sixth batch of Anhui medical team aiding Wuhan for COVID-19. Coronavirus disease 2019 in pregnancy. Int J Infect Dis. 2020;95:376–383. Doi: 10.1016/j.ijid.2020.04.065 https://doi.org/10.1016/j.ijid.2020.04.0...
; China |
28 |
RT-PCR |
30 (18–41) |
3rd (38 GW) |
Fever (5; 17.9%), asthenia (1; 3.6%), cough (7; 25%), dyspnea (2; 7.1%), abdominal pain (5; 17.9%) |
Radiological: bilateral peripheral diffuse ground-glass opacities (26; 92.9%)
Laboratory: Leukocytosis (10; 35.7%), increased CRP (17; 68.0%), lymphopenia (8; 28.6)
|
17 (60.0%) Cesarean delivery
1 (4.3%) Premature birth
4 (14.2%) Induced abortion
2 (7.1%) Severe pneumonia
|
30 |
Lyra et al.(2020)4040 Lyra J, Valente R, Rosário M, Guimarães M. Cesarean section in a pregnant woman with COVID-19: first case in Portugal. Acta Med Port. 2020;33(06):429–431. Doi: 10.20344/amp.13883 https://doi.org/10.20344/amp.13883...
; Portugal |
01 |
RT-PCR |
35 |
3rd (39 GW) |
Cough |
NR |
Cesarean delivery |
31 |
Kelly et al. (2020)4141 Kelly JC, Dombrowksi M, O’Neil-Callahan M, Kernberg AS, Frolova AI, Stout MJ. False-negative testing for severe acute respiratory syndrome coronavirus 2: consideration in obstetrical care. Am J Obstet Gynecol MFM. 2020;2(03):100130. Doi: 10.1016/j.ajogmf.2020.100130 https://doi.org/10.1016/j.ajogmf.2020.10...
; EUA |
01 |
RT-PCR |
– |
3rd (33 GW) |
Vomiting, cough, and tachycardia |
Radiological: Radiography showed subsegmental atelectasis without consolidation
Laboratory: lymphopenia and mild elevation of liver enzymes
|
Cesarean and premature delivery
1 SARS, with the need to undergo invasive mechanical ventilation
|
32 |
Browne et al. (2020)4242 Browne PC, Linfert JB, Perez-Jorge E. Successful treatment of preterm labor in association with acute COVID-19 infection. Am J Perinatol. 2020;37(08):866–868. Doi: 10.1055/s-0040-1709993 https://doi.org/10.1055/s-0040-1709993...
; EUA |
01 |
RT-PCR e Serological (IgG/lgM) |
33 |
2nd (23 GW) |
Fever, cough, and myalgia |
Radiological: NR
Laboratory: leukocytosis
|
Premature cesarean delivery |
33 |
Indraccolo (2020)4343 Indraccolo U. A pregnant woman and the SARS-CoV-2 infection: howare barriers easily crossed? Recenti Prog Med. 2020;111(04): 259–260. Doi: 10.1701/3347.33190 https://doi.org/10.1701/3347.33190...
; Itália |
01 |
RT-PCR |
NR |
3rd (32 GW) |
Cough, epigastric pain, and chest pain |
NR |
NR |
34
|
Lu et al. (2020)4444 LuD, Sang L, Du S, Li T, Chang Y, Yang XA. Asymptomatic COVID-19 infection in late pregnancy indicated no vertical transmission. J Med Virol. 2020;92(09):1660–1664. Doi: 10.1002/jmv.25927 https://doi.org/10.1002/jmv.25927...
; China |
01 |
RT-PCR |
22 |
3rd (38 GW) |
Asymptomatic |
Radiological: bilateral pleural effusion
Laboratory: hyperproteinemia, elevated transaminases and LDH
|
Cesarean delivery |
Total
|
N 412 |
Diagnostic method RTC-PCR (412;100%) |
Average age 27.5 |
|
GA 36.0 |
Symptoms
Fever (49.7%; 205); dyspnea (31.5%; 130); cough (26.5%; 109), fatigue (8.2%; 34); myalgia (7.0%; 29); chest pain (5.5%; 23), diarrhea (4.8%; 20); odynophagia (3.6%; 15)
|
Main radiological findings
Pneumonia/ground-glass pattern (51.4%; 212), 51.5% (172) of which were bilateral
Main laboratory findings
Increased CRP (37.8%; 154);
lymphopenia (20.3%; 84);
leukopenia (14.2%; 58);
neutrophilia (5.5%; 23);
|
Maternal and Gestacional repercussions
Cesarean delivery (36.2%; 149); premature birth (18.4%; 76); abortion (1.0%; 4);
PROM (3.4%; 14); hemorrhage (1.0%; 4); placental abruption (0.2%; 1);p previa (0.2%; 1); severe maternal pneumonia (21.6%; 89); maternal death (0.2%; 1);
Fetal repercussions
Stillborn (0.5%; 2); neonatal death (0.5%; 2); fetal distress (2.7%; 11); fetal bradycardia (0.7%; 3); LBW (1.0%; 4); neonatal COVID infection (1.0%; 4)
|