PURPOSE: the aim of this clinical study of the histological findings in nonpalpable breast lesions managed by surgical excision after wire localization. METHODS: a total of 48 women subjected to 51 preoperative localizations of nonpalpable, mammographically detected breast lesions during August 2001 to April 2005. Indications for biopsy were clustered microcalcifications, solid mass, radiologic parenchymal distortion and focal asymmetries. The lesions were localized preoperatively using hook wire methods, and all biopsies were performed under local anesthesia and venous sedation. RESULTS: histopathology revealed carcinoma in 16 biopsies (31.4%). Noninvasive carcinoma was found in 50% of malignant lesions. Successful lesion sampling was achieved at the first attempt in 100% of cases. Among all malignant lesions, positive-surgical margins were observed in 18.7%. Postoperative complications were a rare event in our series. Suture dehiscence was found in four patients (7.8%). Two of these (3.9%) had local infection. CONCLUSIONS: the hook-wire localization for nonpalpable breast lesions is a simple, accurate and safe method for detection of early breast cancers. The appropriate surgical approach in a single procedure is an excellent method for diagnosis and treatment for early stage, nonpalpable breast carcinoma.
Breast diseases; Breast neoplasms; Biopsy, needle
