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Irreversible visual loss after use of paclitaxel

ABSTRACT

We describe a case of bilateral irreversible visual loss of a 64 year-old patient after prolonged use of paclitaxel. Patient presented best corrected visual acuity of 20/400 in both eyes at first visit and optical coherence tomography showed increased macular in both eyes.After six months of the interruption of -paclitaxel therapy, the patient showed slight improvement of visual acuity reaching 20/200 in both eyes, while OCT demonstrated resolution of macular edema.

Keywords:
Chemotherapy/adverse effects; Paclitaxel/toxicity; Macular edema/chemically induced; Visual acuity/drug effects; Ovarian neoplasms/drug therapy; Case reports

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