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Retinal nerve fiber layer in hepatosplenic schistosomiasis mansoni patients: analysis using optical coherence tomography

Purpose:

To evaluate the retinal nerve fiber layer thickness in patients with the hepatosplenic schistosomiasis mansoni using optical coherence tomography.

Methods:

It was performed a observational, analytic, cross-sectional study. The group of patients enrolled 24 individuals (13 females and 11 males), aged from 27 to 73 years (55.7±11.6 years). In the control group were included 22 subjects (12 females and 10 males) aged from 31 to 77 years (55.4±16.5 years). Of the 92 eyes evaluated, three were excluded because they have opaque media, which made impossible to perform the test. All participants underwent a complete ophthalmologic examination and measurement of the retinal nerve fiber layer using optical coherence tomography.

Results:

The mean thickness of retinal nerve fiber layer was 98.1±15.2µm in the studied group and 114.2±10.0 µm in the control group (p<0.001).

Conclusions:

There was a significant decrease in the retinal nerve fiber layer thickness in all quadrants in patients with hepatosplenic schistosomiasis.

Schistosomiasis; OCT; Eye; Retinal nerve fiber layer


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