ABSTRACT
Retinal detachment (RD) is a common ophthalmic emergency that could bring permanent blindness if it is untreated or treatment is delayed. We conducted a review of Cochrane systematic reviews regarding retinal detachment interventions after a search strategy, we showed and analyzed the data narratively in Ophthalmologic Departure of Escola Paulista de Medicina-UNIFESP. As result, the group of pneumatic retinopexy was less susceptible to choroidal detachment and myopic shift as adverse events when compared with scleral buckle. Although there is no statistically significant difference in visual acuity between standard and heavy silicone oil and between C3F8 and silicone oil, the following interventions may present some benefits for RD: (a)LMWH with 5-FU versus placebo at high-risk of developing postoperative proliferative vitreoretinopathy (PVR); (b) silicone oil was favorable for macular attachment at 2 years compared to sulfur hexafluoride (SF6); (c) Retinal redetachment was reported in fewer participants in the Pars plana vitrectomy (PPV) group compared to the scleral buckling group. So, these points can be considered when choosing the technique to improve better results in cases of retinal detachment. In addition, there is still a need for studies with a prophylactic RD approach and studies with greater evidence of which surgical technique is most appropriate for each indication of RD considering the economic cost and the patient's quality of life.
Keywords:
Retinal detachment; Therapeutics; Evidence-based medicine; Evidence-based practice