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The influence of the laboratory in the treatment of the infectious keratitis

PURPOSE: To evaluate the initial treatment of infectious keratitis, evolution and their correlation with laboratory tests. METHODS: 62 cases of infectious corneal ulcers seen in the Hospital do Servidor Público Estadual - São Paulo underwent Gramstaining and culture for bacterial and fungus. Treatment with fortified Cefalotine (50mg/ml) and Gentamicin (14mg/ml) or fluoroquinolone 0,3% was started. RESULTS: 21 cultures (33,9%) were positive for bacterial infection and 41 (66,1%) showed no growth. Just one case was positive for fungus(1,61%). In 2 cases (3,5%) the Gram staining showed correlation with the culture. Five cases (8,8%) did not respond to the initial treatment and had the medications changed and 91,9% responded to the initial clinical treatment. CONCLUSION: Ours results showed that combination of fortified eye drops or quinolones was efficient to treat infectious corneal ulcers with positive or negative cultures.

Corneal ulcers; Cephalotin; Gentamicins; Ciprofloxacin; Antibacterial agents; Microbial sensitivity tests


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