Lim et al., 20083333 Lim BW, Hinman RS, Wrigley TV, Sharma L, Bennell KL. Does knee malalignment mediate the effects of quadriceps strengthening on knee adduction moment, pain, and function in medial knee osteoarthritis? A randomized controlled trial. Arthritis Rheum 2008;59(07):943–951
|
107 |
48 |
53-73 years old |
GI: 54 GC: 53 |
Quadriceps strengthening with weighted shin sleeves and Theraband |
No intervention |
12 weeks |
Significant pain improvement in the group with better knee alignment |
NA |
K.L. Bennell et al., 20102525 Bennell KL, Hunt MA, Wrigley TV, et al. Hip strengthening reduces symptoms but not knee load in people with medial knee osteoarthritis and varus malalignment: a randomised controlled trial. Osteoarthritis Cartilage 2010;18(05):621–628
|
102 |
51 |
62-73 years old |
GI: 51 GC: 51 |
Hip strengthening l (quadriceps adduction, external rotation, extension and isometry) |
No intervention |
12 weeks |
Pain improvement in GI compared to GC |
Significant hip and quadriceps strength improvement compared to the control group |
G. Kelley Fitzgerald et al., 20112020 Fitzgerald GK, Piva SR, Gil AB, Wisniewski SR, Oddis CV, Irrgang JJ. Agility and perturbation training techniques in exercise therapy for reducing pain and improving function in people with knee osteoarthritis: a randomized clinical trial. Phys Ther 2011;91(04): 452–469
|
183 |
61 |
63-73 years old |
GI:92 GC: 91 |
The agility and disturbance group received the same standard exercise program with the addition of training techniques on agility and disturbance |
Standard exercise program: an exercise program including muscle stretching, strengthening and walking on a treadmill |
4 years and 2 months |
Both groups presented modest improvements, but with no significant differences between them |
NA |
Saccomanno MF et al., 20162121 Saccomanno MF, Donati F, Careri S, Bartoli M, Severini G, Milano G. Efficacy of intra-articular hyaluronic acid injections and exercisebased rehabilitation programme, administered as isolated or integrated therapeutic regimens for the treatment of knee osteoarthritis. Knee Surg Sports Traumatol Arthrosc 2016;24(05): 1686–1694
|
165 |
44 |
40-70 years-old |
GI-1: 53 GI-2:53 GC: 51 |
GI-1: three hyaluronic acid (HA) injectionsGI- 2: HA injections + knee exercises |
Knee exercises |
6 months |
At the 1st month, GI-2 scores were significantly better compared to GI-1. GC and GI-2 presented a significant reduction at the 1st and the 6th month |
NA |
Palmer S et al., 20142222 Palmer S, Domaille M, Cramp F, et al. Transcutaneous electrical nerve stimulation as an adjunct to education and exercise for knee osteoarthritis: a randomized controlled trial. Arthritis Care Res (Hoboken) 2014;66(03):387–394
|
224 |
83 |
60-72 years old |
GI:73 GC-1: 74 GC-2: 77 |
Active TENS (continuous mode, - 110 Hz, 50 µs) + knee exercises |
GC-1: fictional TENS + knee exercises GC-2: knee exercises (30 minutes of education + 30 minutes of exercises) |
6 weeks |
Each score from each group significantly improved over time |
NA |
Holsgaard-Larsen A et al., 20172323 Holsgaard-Larsen A, Clausen B, Sêndergaard J, Christensen R, Andriacchi TP, Roos EM. The effect of instruction in analgesic use compared with neuromuscular exercise on knee-joint load in patients with knee osteoarthritis: a randomized, single-blind, controlled trial. Osteoarthritis Cartilage 2017;25(04):470–480
|
93 |
39 |
40-70 years old |
GI: 47 GC: 46 |
Warming up (10 minutes), functional, proprioceptive training, resistance strengthening and cooling down |
Information about analgesic and anti-inflammatory agents |
8 weeks |
There were no significant differences between groups |
NA |
Jorge RT et al., 20152424 Jorge RT, Souza MC, Chiari A, et al. Progressive resistance exercise in women with osteoarthritis of the knee: a randomized controlled trial. Clin Rehabil 2015;29(03):234–243
|
60 |
NA |
40-70 years old |
GI: 29 GC:31 |
Warming up, 5 minutes at bike. Progressive resistance exercise (knee extension/flexion and hip adduction and abduction with light weights). |
No intervention |
13 weeks |
Pain in the GI group was significantly lower in 45 and 90 days |
Significant differences for hip adduction between groups from T0 until the end of the study |