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Sensitivity and specificity of middle latency potential

The Middle Latency Response (MLR) is a neuroelectrical response that can be recorded in the far field using scalp electrode. Nowadays it is suppose to be one of the best evoked potential for evaluate lesion or dysfunction of the central auditory nervous system. The MLR waves occur between 10 and 80 msec (ms) after the stimulus onset. The Pa is the most reliable because it is the most visible and robust of this potential. Because of the big variability of the amplitude and the latency of the MLR waves it is not yet largely used in the clinical set. AIM: The purpose of this study was to establish the sensitivity and specificity of the MLR waves. STUDY DESIGN: Case-control. MATERIAL AND METHOD: Individuals between 15 and 55 years old with lesion of the central auditory nervous system, with auditory processing disorders and normal one (control group) were evaluated using the MLR. RESULTS: The results showed that the amplitude difference of 30% held the better results, for the electrode as well as the ear effect. The ear effect was more efficient in detecting auditory processing disorder while the electrode effect was better for detecting the lesion.

electrophisiology; evoked potentials; hearing tests; sensitivity; specificity


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