The auditory system has been subject of studies that evaluated its capability to develop plastic responses to different kinds of lesions. Regeneration has been observed in the peripheral portions of the system, with neogenesis of the hair cells in avian, sometimes followed by functional rehabilitation as confirmed by electrophysiological testing. The occurrence of central auditory pathway disorders, secondary to peripheral damage, has been frequently noticed, probably due to a plastic reaction to the lack of afferent signal. A great example of these alterations is found in rodents that develop anomalous motor response to loud sounds, secondary to induced partial deafness, named audiogenic seizures. The authors presented a review about the theme.
auditory system; plasticity; regeneration; audiogenic seizures