Quality of life in adolescents with obsessive-compulsive
disorder

Vivan, Analise de Souza; Rodrigues, Lidiane; Wendt, Guilherme; Bicca, Mônica Giaretton; Cordioli, Aristides Volpato

doi:10.1590/1516-4446-2013-1135

Brasil

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Original Articles • Rev. Bras. Psiquiatr. 35 (4) • Dec 2013 • https://doi.org/10.1590/1516-4446-2013-1135 linkcopy

Quality of life in adolescents with obsessive-compulsive disorder

Authorship SCIMAGO INSTITUTIONS RANKINGS

Objective: To compare adolescents with and without obsessive-compulsive disorder (OCD) with regard to quality of life and to investigate the association between quality of life and clinical characteristics.

Methods: Participants were recruited from an epidemiological study conducted at high schools in the city of Porto Alegre, southern Brazil. The sample comprised 75 adolescents with OCD and 150 without the disorder, aged between 14 and 18 years. Participants were assessed using the following instruments: Schedule for Affective Disorders and Schizophrenia for School Aged Children - Present and Lifetime Version (K-SADS-PL), Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), World Health Organization Quality of Life Assessment - Abbreviated Version (WHOQOL-BREF), Beck Anxiety Inventory (BAI), and Beck Depressive Inventory - II (BDI-II).

Results: The two groups showed significant differences in relation to depression symptoms, anxiety symptoms, and quality of life (all domains), with a poorer performance among adolescents with OCD when compared to those without the disorder. Stepwise regression analysis revealed a significant association between BDI-II scores and quality of life, in all domains.

Conclusions: Our findings suggest that adolescents with OCD, especially those with depression symptoms, have a poorer quality of life when compared with adolescents without OCD.

Obsessive-compulsive disorder; quality of life; adolescents; depression symptoms

Variables	With OCD(n=75)	Without OCD(n=150)	p-value^* * t test.
WHOQOL-BREF
Physical health	62.1±16.3	71.5±14.3	< 0.001
Psychological health	52.1±18.4	64.3±17.0	< 0.001
Social relations	62.6±20.0	70.0±18.6	0.006
Environment	56.0±14.7	63.1±14.9	0.001
Overall	63.0±18.1	71.4±18.1	0.001
BAI	17.8±11.0	9.5±7.5	< 0.001
BDI-II	20.8±11.5	12.6±9.7	< 0.001

Variables	WHOQOL Physical	WHOQOL Psychol	WHOQOL Social	WHOQOL Envir	WHOQOL Overall
Y-BOCS
Obsessions	-0.281^* * p < 0.05;	-0.281^* * p < 0.05;	0.114	0.020	-0.061
Compulsions	-0.101	-0.143	0.062	-0.053	0.017
Total	-0.227^* * p < 0.05;	-0.247^* * p < 0.05;	0.106	-0.024	-0.023
BAI	-0.340^† † p < 0.01;	-0.345^† † p < 0.01;	-0.110	-0.377^† † p < 0.01;	-0.232^* * p < 0.05;
BDI-II	-0.667^‡ ‡ p < 0.001.	-0.807^‡ ‡ p < 0.001.	-0.408^‡ ‡ p < 0.001.	-0.446^‡ ‡ p < 0.001.	-0.517^‡ ‡ p < 0.001.

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Associação Brasileira de Psiquiatria Rua Pedro de Toledo, 967 - casa 1, 04039-032 São Paulo SP Brazil, Tel.: +55 11 5081-6799, Fax: +55 11 3384-6799, Fax: +55 11 5579-6210 - São Paulo - SP - Brazil
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[TFN01t01] BAI = Beck Anxiety Inventory; BDI-II = Beck Depressive Inventory-II; OCD = obsessive-compulsive disorder; WHOQOL-BREF = World Health Organization Quality of Life Assessment - Abbreviated Version.

[TFN02t01] ^*
t test.