1990 |
BR |
Necropsy |
BZDs |
|
X |
|
|
|
|
T, Os and C were susceptible |
Pinheiro & Echevarria (1990)Pinheiro AC, Echevarria FAM. Susceptibilidade de Haemonchus spp. em bovinos ao tratamento anti-helmíntico com albendazole e oxfendazole. Pesq Vet Bras 1990; 10(1-2): 19-21.
|
2001 |
BR |
LDA |
IVM |
X |
|
|
|
|
|
|
Paiva et al. (2001)Paiva F, Sato MO, Acuna AH, Jensen JR, Bressan MCRV. Resistência a ivermectina constatada em Haemonchus placei e Cooperia punctata em bovinos. Hora Vet 2001; 20: 29-32.
|
2001 |
AR |
FECRT and necropsy |
IVM, LA-IVM, DRM, MOX |
X |
|
|
|
|
|
|
Anziani et al. (2001)Anziani OS, Zimmermann G, Guglielmone AA, Vazquez R, Suarez V. Avermectin resistance in Cooperia pectinata in cattle in Argentina. Vet Rec 2001; 149(2): 58-59. http://doi.org/10.1136/vr.149.2.58. PMid:11488345. http://doi.org/10.1136/vr.149.2.58...
|
2001 |
AR |
FECRT and necropsy |
IVM, LA-IVM, DRM, |
X |
|
|
|
|
|
MOX and FBZ: efficacy >95%. |
Fiel et al. (2001)Fiel CA, Saumell CA, Steffan PE, Rodriguez EM. Resistance of Cooperia to ivermectin treatments in grazing cattle of the Humid Pampa, Argentina. Vet Parasitol 2001; 97(3): 211-217. http://doi.org/10.1016/S0304-4017(01)00407-1. PMid:11390073. http://doi.org/10.1016/S0304-4017(01)004...
|
2003 |
AR |
FECRT and necropsy |
IVM and BZD |
X |
X |
|
|
X |
|
|
Mejía et al. (2003)Mejía ME, Fernández Igartúa BM, Schmidt EE, Cabaret J. Multispecies and multiple anthelmintic resistance on cattle nematodes in a farm in Argentina: the beginning of high resistance? Vet Res 2003; 34(4): 461-467. http://doi.org/10.1051/vetres:2003018. PMid:12911862. http://doi.org/10.1051/vetres:2003018...
|
2004 |
AR |
FECRT |
IVM and BZD |
X |
X |
|
|
|
|
LEV: efficacy >95% |
Anziani et al. (2004)Anziani OS, Suarez VH, Guglielmone AA, Warnke O, Grande H, Coles GC. Resistance to benzimidazole and macrocyclic lactone anthelmintics in cattle nematodes in Argentina. Vet Parasitol 2004; 122(4): 303-306. http://doi.org/10.1016/j.vetpar.2004.05.018. PMid:15262008. http://doi.org/10.1016/j.vetpar.2004.05....
|
2004 |
AR |
FECRT |
AVMs |
X |
|
|
|
|
|
|
Anziani & Fiel (2004)Anziani OS, Fiel CA. Estado actual de la resistência anti-helmíntica (nematodos gastrointestinaems) en bovinos de la Argentina. Vet Argent 2004; 21: 86-101.
|
2005 |
BR |
FECRT |
IVM and DRM |
|
X |
|
|
|
|
MOX and ABA: efficacy >99% |
Rangel et al. (2005)Rangel VB, Leite RC, Oliveira PR, Santos EJ Jr. Resistência de Cooperia spp. e Haemonchus spp. às avermectinas em bovinos de corte. Arq Bras Med Vet Zootec 2005; 57(2): 186-190. http://doi.org/10.1590/S0102-09352005000200008. http://doi.org/10.1590/S0102-09352005000...
|
2006 |
BR |
FECRT |
IVM, ABA, DRM and MOX |
X |
|
|
|
|
X |
H susceptible to ABA |
Mello et al. (2006)Mello MHA, Depner R, Molento MB, Ferreira JJ. Resistência lateral às macrolactonas em nematodas de bovinos. Arch Vet Sci 2006; 11(1): 8-12. http://doi.org/10.5380/avs.v11i1.5628. http://doi.org/10.5380/avs.v11i1.5628...
|
2007 |
BR |
FECRT |
IVM, AS and LEV |
X |
X |
|
|
|
|
25 farms. Percentage of farms with FECRT< 90%: IVM-92%, LEV-20%, AS-8%, MOX-0% |
Soutello et al. (2007)Soutello RGV, Seno MC, Amarante AF. Anthelmintic resistance in cattle nematodes in northwestern São Paulo State, Brazil. Vet Parasitol 2007; 148(3-4): 360-364. http://doi.org/10.1016/j.vetpar.2007.06.023. PMid:17656022. http://doi.org/10.1016/j.vetpar.2007.06....
|
2007 |
AR |
FECRT |
IVM and BZD |
X |
|
|
|
X |
|
25 farms. Percentage of farms with AHR: IVM-60%, FBZ-32%, LEV-0%. |
Suarez & Cristel (2007)Suarez VH, Cristel SL. Anthelmintic resistance in cattle nematode in the western Pampeana Region of Argentina. Vet Parasitol 2007; 144(1-2): 111-117. http://doi.org/10.1016/j.vetpar.2006.09.016. PMid:17049746. http://doi.org/10.1016/j.vetpar.2006.09....
|
2008 |
BR |
FECRT |
IVM, AS and LEV |
X |
X |
|
|
|
|
39 farms. Percentage of farms with AHR: IVM-82.1%, LEV-15.4% and AS-7.8% |
Souza et al. (2008)Souza AP, Ramos CI, Bellato V, Sartor AP, Schelbauer CA. Resistência de helmintos gastrintestinais de bovinos a anti-helmínticos no Planalto Catarinense. Cienc Rural 2008; 38(5): 1363-1367. http://doi.org/10.1590/S0103-84782008000500026. http://doi.org/10.1590/S0103-84782008000...
|
2008 |
BR |
Necropsy |
IVM and DRM |
X |
|
|
|
|
|
|
Cardoso et al. (2008)Cardoso JMS, Martins IVF, Sant’anna FB, Correia TR, Tancredi IP, Coumendouros K, et al. Identification of ivermectin and doramectin-resistant Cooperia punctata (Linstow, 1907) in a dairy herd in the State of Rio de Janeiro, Brazil. Braz J Vet Res Anim Sci 2008; 45(Suppl.): 75-81. http://doi.org/10.11606/S1413-95962008000700010. http://doi.org/10.11606/S1413-9596200800...
|
2009 |
BR |
Necropsy |
MOX |
X |
|
|
X |
|
|
H susceptible to MOX |
Condi et al. (2009)Condi GK, Soutello RGV, Amarante AFT. Moxidectin-resistant nematodes in cattle in Brazil. Vet Parasitol 2009; 161(3-4): 213-217. http://doi.org/10.1016/j.vetpar.2009.01.031. PMid:19251366. http://doi.org/10.1016/j.vetpar.2009.01....
|
2009 |
BR |
Necropsy |
IVM and LA-IVM |
X |
X |
|
X |
|
X |
High efficacy of Trichlorfon |
Lopes et al. (2009)Lopes WDZ, Santos TR, Borges FA, Sakamoto CA, Soares VE, Costa GH, et al. Anthelmintic efficacy of oral trichlorfon solution against ivermectin resistant nematode strains in cattle. Vet Parasitol 2009; 166(1-2): 98-102. http://doi.org/10.1016/j.vetpar.2009.07.045. PMid:19709817. http://doi.org/10.1016/j.vetpar.2009.07....
|
2010 |
BR |
FECRT |
IVM, LA-IVM, ABA and DRM |
X |
X |
|
|
X |
X |
Os was resistant only to IVM. MOX and SA: efficacy >95% |
Cezar et al. (2010)Cezar AS, Vogel FSF, Sangioni LA, Antonello AM, Camillo G, Toscan G, et al. Ação anti-helmíntica de diferentes formulações de lactonas macrocíclicas em cepas resistentes de nematódeos de bovinos. Pesq Vet Bras 2010; 30(7): 523-528. http://doi.org/10.1590/S0100-736X2010000700002. http://doi.org/10.1590/S0100-736X2010000...
|
2010 |
BR |
FECRT |
IVM |
X |
|
|
|
|
|
MOX and SA: efficacy >95% |
Soutello et al. (2010)Soutello RVG, Coelho WMD, Oliveira FP, Fonzar JF, Luquetti BC, Souza RFP, et al. Evaluation of reduction in egg shedding of gastrointestinal nematodes in cattle following administration of anthelmintics. Rev Bras Parasitol Vet 2010; 19(3): 183-185. http://doi.org/10.1590/S1984-29612010000300011. PMid:20943024. http://doi.org/10.1590/S1984-29612010000...
|
2010 |
AR |
FECRT |
IVM and MOX |
X |
|
|
|
|
|
|
Lifschitz et al. (2010)Lifschitz A, Suarez VH, Sallovitz J, Cristel SL, Imperiale F, Ahoussou S, et al. Cattle nematodes resistant to macrocyclic lactones: comparative effects of P-glycoprotein modulation on the efficacy and disposition kinetics of ivermectin and moxidectin. Exp Parasitol 2010; 125(2): 172-178. http://doi.org/10.1016/j.exppara.2010.01.009. PMid:20109455. http://doi.org/10.1016/j.exppara.2010.01...
|
2011 |
BR |
FECRT |
IVM, LA-IVM, AS, ABA and DRM |
X |
X |
|
|
|
|
High frequency of treatments (8 treatments/2 years). Dairy cattle. |
Costa et al. (2011)Costa MSVLF, Araújo RN, Costa AJLF, Simões RF, Lima WS. Anthelmintic resistance in a dairy cattle farm in the State of Minas Gerais. Rev Bras Parasitol Vet 2011; 20(2): 115-120. http://doi.org/10.1590/S1984-29612011000200005. PMid:21722485. http://doi.org/10.1590/S1984-29612011000...
|
2011 |
AR |
Necropsy |
IVM |
X |
|
X |
|
|
X |
|
Fiel et al. (2011)Fiel C, Guzmán M, Steffan P, Prieto O, Bhushan C. Comparative efficacy of trichlorphon and trichlorphon/ivermectin combination treatment against anthelmintic-resistant cattle nematodes in Argentina. Parasitol Res 2011;109(Suppl. 1): 105-112. http://doi.org/10.1007/s00436-011-2407-3. PMid:21739380. http://doi.org/10.1007/s00436-011-2407-3...
|
2012 |
BR |
FECRT |
IVM and DRM |
N.I. |
N.I. |
N.I. |
N.I. |
N.I. |
N.I. |
ABA and SA: efficacy >95% |
Bruhn et al. (2013)Bruhn FRP, Lopes MA, Perazza CA, Demeu FA, Santos G, Franco A No, et al. Eficiência técnica e econômica da aplicação de diferentes anti-helmínticos em fêmeas da raça holandesa na fase de recria durante o outono-inverno de 2009. Acta Tecnol 2013; 7(2): 25-30. http://doi.org/10.35818/acta.v7i2.138. http://doi.org/10.35818/acta.v7i2.138...
|
2013 |
BR |
FECRT |
IVM, LA-IVM and LA-DRM |
X |
X |
|
|
|
|
|
Borges et al. (2013)Borges FA, Almeida GD, Heckler RP, Lemes RT, Onizuka MKV, Borges DGL. Anthelmintic resistance impact on tropical beef cattle productivity: effect on weight gain of weaned calves. Trop Anim Health Prod 2013; 45(3): 723-727. http://doi.org/10.1007/s11250-012-0280-4. PMid:23076819. http://doi.org/10.1007/s11250-012-0280-4...
|
2013 |
BR |
LMIT |
IVM |
X |
|
|
|
|
|
8 farms. 100% of isolates were resistant. |
Almeida et al. (2013)Almeida GD, Feliz DC, Heckler RP, Borges DG, Onizuka MKV, Tavares LER, et al. Ivermectin and moxidectin resistance characterization by larval migration inhibition test in field isolates of Cooperia spp. in beef cattle, Mato Grosso do Sul, Brazil. Vet Parasitol 2013; 191(1-2): 59-65. http://doi.org/10.1016/j.vetpar.2012.08.012. PMid:22963710. http://doi.org/10.1016/j.vetpar.2012.08....
|
2014 |
BR |
Necropsy |
LA-IVM |
X |
X |
|
X |
|
|
6 farms. |
Felippelli et al. (2014)Felippelli G, Lopes WDZ, Cruz BC, Teixeira WFP, Maciel WG, Fávero FC, et al. Nematode resistance to ivermectin (630 and 700μg/kg) in cattle from the Southeast and South of Brazil. Parasitol Int 2014; 63(6): 835-840. http://doi.org/10.1016/j.parint.2014.08.001. PMid:25130588. http://doi.org/10.1016/j.parint.2014.08....
|
2014 |
BR |
FECRT |
IVM, MOX and AS |
X |
X |
|
X |
|
X |
10 farms. Percentage of farms with AHR: IVM-100%, MOX-80%, LEV-10% and AS-10%. Mean efficacy of MOX>80%. |
Neves et al. (2014)Neves JH, Carvalho N, Rinaldi L, Cringoli G, Amarante AFT. Diagnosis of anthelmintic resistance in cattle in Brazil: a comparison of different methodologies. Vet Parasitol 2014; 206(3-4): 216-226. http://doi.org/10.1016/j.vetpar.2014.10.015. PMid:25468021. http://doi.org/10.1016/j.vetpar.2014.10....
|
2014 |
BR |
Necropsy |
IVM |
X |
X |
|
X |
|
|
|
Lopes et al. (2014a)Lopes WDZ, Felippelli G, Teixeira WFP, Cruz BC, Maciel WG, Buzzulini C, et al. Resistência de Haemonchus placei, Cooperia punctata e Oesophagostomum radiatum à ivermectina pour-on a 500mcgkg-1 em rebanhos bovinos no Brasil. Cienc Rural 2014a; 44(5): 847-853. http://doi.org/10.1590/S0103-84782014000500014. http://doi.org/10.1590/S0103-84782014000...
|
2014 |
BR |
Necropsy |
LA-IVM |
X |
X |
|
|
|
|
MOX: efficacy >95% |
Lopes et al. (2014b)Lopes WDZ, Teixeira WFP, Felippelli G, Cruz BC, Maciel WG, Soares VE, et al. Assessing resistance of ivermectin and moxidectin against nematodes in cattle naturally infected using three different methodologies. Res Vet Sci 2014b; 96(1): 133-138. http://doi.org/10.1016/j.rvsc.2013.11.001. PMid:24290235. http://doi.org/10.1016/j.rvsc.2013.11.00...
|
2014 |
AR |
FECRT |
IVM and MOX |
X |
|
|
|
|
|
LEV+RBZ: efficacy = 99% |
Fazzio et al. (2014)Fazzio LE, Sánchez RO, Streitenberger N, Galvan WR, Giudici CJ, Gimeno EJ. The effect of anthelmintic resistance on the productivity in feedlot cattle. Vet Parasitol 2014; 206(3-4): 240-245. http://doi.org/10.1016/j.vetpar.2014.10.010. PMid:25468022. http://doi.org/10.1016/j.vetpar.2014.10....
|
2015 |
BR |
Necropsy |
IVM, LA-IVM and LA-DRM |
X |
X |
|
X |
|
|
|
Borges et al. (2015)Borges FA, Borges DGL, Heckler RP, Neves JPL, Lopes FG, Onizuka MKV. Multispecies resistance of cattle gastrointestinal nematodes to long-acting avermectin formulations in Mato Grosso do Sul. Vet Parasitol 2015; 212(3-4): 299-302. http://doi.org/10.1016/j.vetpar.2015.06.015. PMid:26129974. http://doi.org/10.1016/j.vetpar.2015.06....
|
2015 |
BR |
FECRT |
LA-IVM |
X |
X |
|
X |
|
X |
|
Holsback et al. (2015)Holsback L, Silva MA, Patelli THC, Jesus AP, Sanches JR. Resistance of Haemonchus, Cooperia, Trichostrongylus, and Oesophagostomum to ivermectin in dairy cattle in Paraná. Semina: Ciênc Agrár 2015;36(3 Suppl. 1): 2031-2036. http://doi.org/10.5433/1679-0359.2015v36n3Supl1p2031. http://doi.org/10.5433/1679-0359.2015v36...
|
2016 |
BR |
FECRT |
IVM, DRM, EPR, FBZ, CLO, NIT, DIS, LEV, AS and MOX |
X |
X |
|
|
|
X |
11 farms. Combinations MOX+LEV, DRM+FBZ and LEV+CLO: efficacy>95%. |
Ramos et al. (2016)Ramos F, Portella LP, Rodrigues FS, Reginato CZ, Pötter L, Cezar AS. Anthelmintic resistance in gastrointestinal nematodes of beef cattle in the state of Rio Grande do Sul, Brazil. Int J Parasitol Drugs Drug Resist 2016; 6(1): 93-101. http://doi.org/10.1016/j.ijpddr.2016.02.002. PMid:27054068. http://doi.org/10.1016/j.ijpddr.2016.02....
|
2016 |
BR |
FECRT |
DRM, MOX and LEV |
X |
X |
|
|
|
|
|
Heckler et al. (2016)Heckler RP, Borges DGL, Vieira MC, Conde MH, Green M, Amorim ML, et al. New approach for the strategic control of gastrointestinal nematodes in grazed beef cattle during the growing phase in central Brazil. Vet Parasitol 2016; 221: 123-129. http://doi.org/10.1016/j.vetpar.2016.03.010. PMid:27084483. http://doi.org/10.1016/j.vetpar.2016.03....
|
2017 |
AR |
FECRT |
IVM |
X |
X |
|
|
|
|
|
Canton et al. (2017)Canton C, Ceballos L, Fiel C, Moreno L, Domingo Yagüez P, Bernat G, et al. Resistant nematodes in cattle: pharmaco-therapeutic assessment of the ivermectin-ricobendazole combination. Vet Parasitol 2017; 234: 40-48. http://doi.org/10.1016/j.vetpar.2016.12.021. PMid:28115181. http://doi.org/10.1016/j.vetpar.2016.12....
|
2017 |
AR |
FECRT |
IVM |
X |
X |
|
|
X |
|
62 farms. Percentage of farms with AHR (genus): IVM-93.5% (C and H), RBZ-27.9% (C and Os), FBZ-7.4 (H), LEV-0%. |
Cristel et al. (2017)Cristel S, Fiel C, Anziani O, Descarga C, Cetrá B, Romero J, et al. Anthelmintic resistance in grazing beef cattle in central and northeastern areas of Argentina: an update. Vet Parasitol Reg Stud Rep 2017; 9: 25-28. http://doi.org/10.1016/j.vprsr.2017.04.003. PMid:31014837. http://doi.org/10.1016/j.vprsr.2017.04.0...
|
2018 |
AR |
FECRT |
IVM |
X |
|
|
|
|
|
|
Canton et al. (2018)Canton C, Ceballos L, Domínguez MP, Moreno L, Fiel C, Bernat G, et al. Pharmaco-parasitological evaluation of the ricobendazole plus levamisole nematodicidal combination in cattle. J Vet Pharmacol Ther 2018; 41(1): 83-91. http://doi.org/10.1111/jvp.12438. PMid:28695609. http://doi.org/10.1111/jvp.12438...
|
2020 |
BR |
FECRT |
MLs and AS |
X |
X |
|
|
|
|
LEV: efficacy>95% |
Pivoto et al. (2020a)Pivoto FL, Cezar AS, Vogel FSF, Marques CB, Alves MEM, Becker CC, et al. Economic losses caused by the use of low-efficacy anthelmintic drugs in growing heifers. Trop Anim Health Prod 2020a; 52(3): 1365-1374. http://doi.org/10.1007/s11250-019-02144-1. PMid:31758387. http://doi.org/10.1007/s11250-019-02144-...
|
2020 |
BR |
FECRT |
LMs |
X |
X |
|
|
|
|
A case of clinical helminthosis culminating in the death of steers. LEV and AS: efficacy>95% |
Pivoto et al. (2020b)Pivoto FL, Cezar AS, Vogel FSF, Leal MLR. Effects of long-term indiscriminate use of macrocyclic lactones in cattle: parasite resistance, clinical helminthosis, and production losses. Vet Parasitol Reg Stud Rep 2020b; 20: 100381. http://doi.org/10.1016/j.vprsr.2020.100381. PMid:32448543. http://doi.org/10.1016/j.vprsr.2020.1003...
|
2020 |
BR |
FECRT |
IVM |
X |
X |
|
|
|
|
BZDs: efficacy>95% |
Neves et al. (2020)Neves JH, Carvalho N, Amarante AFT. Gastrointestinal nematode infections do not hinder the development of Simmental × Nellore crossbred calves raised with a nutritionally enhanced diet. Rev Bras Parasitol Vet 2020; 29(1): e015819. http://doi.org/10.1590/s1984-29612020006. PMid:32236331. http://doi.org/10.1590/s1984-29612020006...
|
2021 |
BR |
FECRT |
|
|
|
|
|
|
|
FBZ: efficacy=100% |
Nakatani et al. (2021)Nakatani MTM, Conde MH, Freitas MG, Fávero FC, Paula LC, Cabrera MS, et al. Economic viability analysis of an oral anthelmintic treatment for cattle in feedlot. J Agric Stud 2021; 9(2): 188-204. http://doi.org/10.5296/jas.v9i2.18032. http://doi.org/10.5296/jas.v9i2.18032...
|
2021 |
BR |
FECRT |
IVM |
X |
X |
|
|
|
|
BZDs: efficacy>95% |
Neves et al. (2021)Neves JH, Carvalho N, Santos NC, Ratti J Jr, Martins CL, Amarante AFT. Effect of antihelminths with contrasting efficacy against gastrointestinal nematodes on the live-weight gain of young Nellore cattle. Vet Parasitol Reg Stud Rep 2021; 25: 100597. http://doi.org/10.1016/j.vprsr.2021.100597. PMid:34474790. http://doi.org/10.1016/j.vprsr.2021.1005...
|
2021 |
BR |
FECRT |
IVM, BZD, CLO |
N.I. |
20 farms. Percentage of farms with AHR: IVM-95%, AS-95%, CLO-75% and LEV-20%. |
Melo et al. (2021)Melo LRB, Sousa LC, Menezes Oliveira CS, Alvares FBV, Ferreira LC, Bezerra RA, et al. Resistance of bovine gastrointestinal nematodes to four classes of anthelmintics in the semiarid region of Paraíba state, Brazil. Rev Bras Parasitol Vet 2021; 30(3): e010921. http://doi.org/10.1590/s1984-29612021077. PMid:34550213. http://doi.org/10.1590/s1984-29612021077...
|
2022 |
BR |
FECRT |
LA-IVM |
X |
X |
|
|
|
|
A case of clinical helminthosis culminating in the death of cattle. |
Lima et al. (2022)Lima SC, Borges DGL, Pupin RC, Guizelini CC, Paula JPL, Borges FA, et al. Mortality caused by gastrointestinal nematodes in beef cattle submitted to an inadequate sanitary protocol. Pesq Vet Bras 2022; 42: e07030. http://doi.org/10.1590/1678-5150-pvb-7030. http://doi.org/10.1590/1678-5150-pvb-703...
|
2022 |
BR |
FECRT |
IVM, LA-IVM, MOX |
X |
X |
|
|
|
|
|
Borges et al. (2022)Borges DGL, Conde MH, Cunha CCT, Freitas MG, Moro E, Borges FA. Moxidectin: a viable alternative for the control of ivermectin-resistant gastrointestinal nematodes in beef cattle. Acta Vet 2022; 72(1): 16-29. http://doi.org/10.2478/acve-2022-0002. http://doi.org/10.2478/acve-2022-0002...
|