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Review articles • Rev. Bras. Reumatol. 57 (6) • Nov-Dec 2017 • https://doi.org/10.1016/j.rbre.2016.05.003   copy

Three cases of anti-TNF induced myositis and literature review

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstract

Anti-tumor necrosis factor drugs are frequently preferred in the treatment of rheumatologic diseases and other inflammatory diseases. The development of myositis after using anti-tumor necrosis factor drugs is a rare clinical condition. Here we aimed to report cases who developed myositis after using anti-tumor necrosis factor drugs and review the current literature. We report two cases of rheumatoid arthritis and a case of ankylosing spondylitis developed idiopathic inflammatory myopathy following anti-tumor necrosis factor therapy. In conclusion, myositis could develop during anti-tumor necrosis factor therapy, so these patients should be evaluated carefully initially for myositis and should be closely monitored due to the potential for developing myositis in treatment process.

Keywords:
Anti-tumor necrosis factor (anti-TNF) drugs; Myositis; Jo-1

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