Drug |
NCT01504867 |
Acid acetilsalicilic |
LIPS-A: Lung Injury Prevention Study with Aspirin |
Ognjen Gajic/Beth Israel Deaconess Medical Center/Montefiore Medical Center/Vanderbilt University/Mayo Clinic |
400 |
Drug |
NCT01659307 |
Acid acetilsalicilic |
The Effect of Aspirin on Reducing Inflammation in Human in Vivo Model of Acute Lung Injury |
Belfast Health and Social Care Trust/The Intensive Care Society United Kingdom/Northern Ireland Clinical Trials Unit/Queen's University, Belfast |
33 |
Drug |
NCT00112164 |
Activated protein C |
Activated Protein C to Treat Acute Lung Injuries |
University of California, San Francisco/National Heart, Lung, and Blood Institute (NHLBI) |
90 |
Drug |
NCT02106975 |
Ascorbic acid |
Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury |
Virginia Commonwealth University/National Heart, Lung, and Blood Institute (NHLBI) |
170 |
Drug |
NCT01434121 |
Ascorbic acid |
Ascorbic Acid (Vitamin C) Infusion in Human Sepsis |
Virginia Commonwealth University |
24 |
Drug |
NCT01050699 |
Dexmedetomidine |
Sleep Intervention During Acute Lung Injury |
University of Arizona/National Heart, Lung, and Blood Institute (NHLBI) |
90 |
Drug |
NCT00351533 |
Fish oil |
A Phase II Randomized Trial of Fish Oil in Patients with Acute Lung Injury (ALI) |
University of Washington/National Heart, Lung, and Blood Institute (NHLBI)/American Thoracic Society|Acute Respiratory Distress Syndrome Foundation/American Society for Parenteral and Enteral Nutrition |
90 |
Drug |
NCT01335932 |
Gancliclovir/Valganciclovir |
Study of Ganciclovir/Valganciclovir for Prevention of Cytomegalovirus Reactivation in Acute Injury of the Lung and Respiratory Failure |
Fred Hutchinson Cancer Research Center/National Heart, Lung, and Blood Institute (NHLBI)/Genentech, Inc. |
160 |
Drug |
NCT01713309 |
Heparin binding protein |
Heparin Binding Protein in Patients with Acute Respiratory Failure Treated with GCSF (Filgrastim) |
Helsinki University Central Hospital/The Swedish Research Council |
59 |
Drug |
NCT02425579 |
Inhaled carbon monoxide |
Safety Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS) |
Weill Medical College of Cornell University/Brigham and Women's Hospital/Massachusetts General Hospital/Duke University |
48 |
Drug |
NCT00605696 |
Insulin |
Evaluating the Effectiveness of Early Insulin Therapy in People at Risk for Developing Acute Lung Injury/Acute Respiratory Distress Syndrome |
National Heart, Lung, and Blood Institute (NHLBI) |
90 |
Drug |
NCT01096771 |
Intravenous lipids |
The Effect of Intravenous Lipids on Lung Function in Acute Respiratory Distress Syndrome (ARDS) |
Methodist Research Institute, Indianapolis |
14 |
Drug |
NCT01938079 |
Ketamine |
Pharmacokinetic Alterations During ECMO |
Columbia University |
20 |
Drug |
NCT00159510 |
Methylene blue & nitric oxide |
Studies of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome |
Northern State Medical University/Helse Nord |
28 |
Drug |
NCT00655928 |
N-acetylcysteine |
Modulation of Lung Injury Complicating Lung Resection |
Imperial College London/Royal College of Physicians/Royal Brompton & Harefield NHS Foundation Trust |
47 |
Drug |
NCT01573715 |
Neuromuscular blocking agents |
Effects of Neuromuscular Blocking Agents (NMBA) on the Alteration of Transpulmonary Pressures at the Early Phase of Acute Respiratory Distress Syndrome (ARDS) |
Assistance Publique Hopitaux De Marseille |
40 |
Drug |
NCT00299650 |
Neuromuscular blocking agents |
Systematic Early Use of Neuromuscular Blocking Agents in ARDS Patients |
Assistance Publique Hopitaux de Marseille/GlaxoSmithKline |
340 |
Drug |
NCT02509078 |
Neuromuscular blocking agents |
Reevaluation of Systemic Early Neuromuscular Blockade |
Massachusetts General Hospital/National Heart, Lung, and Blood Institute (NHLBI) |
1408 |
Drug |
NCT00036062 |
Neutrophil elastase inhibitor |
A Phase II Study to Determine the Efficacy and Safety of Sivelestat in Subjects with Acute Lung Injury |
Eli Lilly and Company |
600 |
Drug |
NCT00219375 |
Neutrophil elastase inhibitor |
Study of Sivelestat Sodium Hydrate in Acute Lung Injury (ALI) Associated with Systemic Inflammatory Response Syndrome (SIRS) in Japan |
Ono Pharmaceutical Co. Ltd |
649 |
Drug |
NCT01391481 |
Perfluorocarbon inhaled |
Perfluorocarbon (PFC) Inhalation Treatment of Acute Lung Injury/Acute Respiratory Distress Syndrome |
Chinese PLA General Hospital/The Second Artillery General Hospital/The 306 Hospital of People's Liberation Army/First Hospitals affiliated to the China PLA General Hospital/General Hospital of Chinese Armed Police Forces/Beijing Shijitan Hospital/Air Force |
200 |
Drug |
NCT02370095 |
Prostaciclin analogue |
Treprostinil Sodium Inhalation for Patients at High Risk for ARDS |
--- |
NR |
Drug |
NCT01274481 |
Prostaciclin analogue |
Iloprost Effects on Gas Exchange and Pulmonary Mechanics |
University of Oklahoma/Actelion |
20 |
Drug |
NCT00455767 |
Protein inhibitor of human neutrophil elastase |
Safety and Efficacy Study of Depelestat in Acute Respiratory Distress Syndrome (ARDS) Patients |
Debiopharm International SA |
84 |
Drug |
NCT01597635 |
Recombinant human angiotensin converting enzyme type 2 |
The Safety, Tolerability, PK and PD of GSK2586881 in Patients with Acute Lung Injury |
GlaxoSmithKline |
43 |
Drug |
NCT00996840 |
Selective inhibitor of p38 alpha (MAPK) |
SB-681323 IV for Subjects at Risk of Acute Lung Injury or ARDS |
GlaxoSmithKline |
90 |
Drug |
NCT02166853 |
Sevofluorane |
Effects of SEvoflurane on Gas Exchange and Inflammation in Patients with ARDS (SEGA Study) |
University Hospital, Clermont-Ferrand |
50 |
Drug |
NCT01619280 |
Sodium nitroprrusside |
Safety Study of Nebulized Sodium Nitroprusside in Adult Acute Lung Injury |
Mount Sinai Hospital, Canada |
30 |
Drug |
NCT00979121 |
Statins |
Statins for Acutely Injured Lungs from Sepsis |
National Heart, Lung, and Blood Institute (NHLBI) |
745 |
Drug |
NCT00562835 |
Steroids |
Steroids in Patients with Early ARDS |
Catholic University of the Sacred Heart |
400 |
Drug |
NCT00773058 |
Steroids |
Effect of Treatment with Stress-Doses Glucocorticoid in Patients with Acute Respiratory Distress Syndrome (ARDS) |
Southeast University, China/Nanjing Medical University |
100 |
Drug |
NCT01284452 |
Steroids |
Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients with Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) |
Mahidol University |
197 |
Drug |
NCT00290602 |
Steroids |
Early Low Dose Steroid Therapy of Acute Respiratory Distress Syndrome |
National Cancer Center, Korea |
40 |
Drug |
NCT01783821 |
Steroids |
LIPS-B: Lung Injury Prevention Study with Budesonide and Beta |
Mayo Clinic/Stanford University/Beth Israel Deaconess Medical Center/University of Arizona/National Center for Research Resources (NCRR) |
61 |
Drug |
NCT02819453 |
Steroids |
Corticosteroid Mediates Acute Respiratory Distress Syndrome |
Shanghai Pulmonary Hospital, Shanghai, China |
20 |
Drug |
NCT00127985 |
Steroids |
6-Methyl-Prednisolone for Multiple Organ Dysfunction Syndrome |
Hospital Universitario Principe de Asturias|Pfizer |
240 |
Drug |
NCT00742482 |
Surfactant |
Efficacy and Safety of 3 Doses of HL10 Given at Fixed Time Intervals Compared to Standard Therapy |
LEO Pharma |
418 |
Drug |
NCT01462279 |
Thiamine |
Effect of Thiamine on Oxygen Utilization (VO2) in Critical Illness |
Beth Israel Deaconess Medical Center/American Medical Association |
20 |
Drug |
NCT02895191 |
Urinary trypsin inhibitor |
The Safety and Dose Response Relationship of Ulinastatin for Acute Respiratory Distress Syndrome (ARDS) |
Techpool Bio-Pharma Co., Ltd./The First Affiliated Hospital of Guangzhou Medical University |
60 |
Drug |
NCT00004494 |
Vasoactive intestinal peptide |
Phase I Study of Vasoactive Intestinal Peptide in Patients with Acute Respiratory Distress Syndrome and Sepsis |
Stony Brook University/State University of New York/FDA Office of Orphan Products Development |
18 |
Drug |
NCT02468531 |
Xenon anesthesia |
The Clinic Trial on Protection of Xenon Anaesthesia Against Perioperative Acute Lung Injury for Standford an Acute Aortic Dissection |
Beijing Anzhen Hospital |
80 |