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Concomitance of Hashimoto's thyroiditis and differentiated thyroid cancer

BACKGROUND: In spite of the controversial statistical relationship, the association of Hashimoto thyroiditis and differentiated carcinoma seems to be increasing. OBJECTIVE: To assess the association of Hashimoto thyroidites and differentiated carcinoma at Santa Casa de Misericórdia de Goiânia, Goiás. METHODS: From 1395 thyroidectomies performed from 1994 to 2003, 120 differentiated carcinoma (27 folicular and 93 papillary) were selected, analyzing clinical features (age and gender) with presentation of the frequency and a summary of measure resume in statistical description. For evaluation of auto-immune disease and differentiated carcinoma, contingence tables and analysis through non parametric test of Pearson K Square testwere employedc, with a level of significance of 5% (p less than 0.05%). RESULTS: We found a frequency of association of four times between Hashimoto thyroiditis and differentiated carcinoma of the thyroid in relation to others thyroid pathologies (16.7% versus 3.6%). CONCLUSION: These results allow us the conclusion that this association in not casual, suggesting a clinical and laboratorial follow up in patients with auto-immune diseases.

Thyroiditis; Thyroid neoplasms; Thyroiditis; autoimmune


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