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Relationship between ovariectomy and body weight in an experimental model

BACKGROUND: Assess the effects of the ovarian hormones privation on the body weight, in experimental model. METHODS: Forty adult female rats were randomly divided into three groups: Group 1 (n=10) - control, Group 2 (n=10) -sham operation, Group 3 (n=20) - ovariectomy. The weight of the animals was weekly assessed during 30 weeks and the results were compared by Student t test, with significance for p < 0.05. RESULTS: The ovariectomized rats presented higher weight gain than those of the other groups. The difference was significant after nine weeks, until the end of the experiment. CONCLUSION: In the present work, privation of the ovarian hormones was related to higher body weight, in rats.

Ovariectomy; Body weight; Estradiol; Progesterone; Female Rat


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