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Applicability of mismatch negativity in children and teenagers: a descriptive review

ABSTRACT

Mismatch Negativity (MMN) is a cortical potential that occurs in response to a modification of an acoustic stimulus from a sequence of repeated stimuli, which reflects the brain capacity in relation to the discrimination of the sound passively, in other words, without the need of attention of the subject to the sound stimulus. Then, the aim of this study is to perform a descriptive review on MMN, in order to identify its applicability in children and teenagers, in the last five years. To this end, the search was performed in the Lilacs, SciELO, Medline and Pubmed databases by using the following descriptors: córtex auditivo, eletrofisiologia, potenciais evocados auditivos (the English version would be: auditory cortex, electrophysiology, auditory evoked potentials). In addition to, the words Mismatch and Negativity were used. In this review, we found 14 studies which evaluated children and/or teenagers with difficulty in speech articulation, specific language impairment, auditory processing disorder, Attention Deficit and Hyperactivity Disorder (ADHD), dyslexia, autism, risk for schizophrenia, psychosis, amusia, phenylketonuria and selective attention. So, it was possible to perform the descriptive review on the application of MMN in children and teenagers, concluding that in the last five years there were a reasonable article production about the theme. However, studies on this topic are not expressive in Brazil. Even though there is a variety of applications to MMN, in relation to the Brazilian population, there is a need for scientific evidences to use this potential in different age groups. We also verified that the search for MMN studies in the databases could be performed by only using the words Mismatch and Negativity.

Keywords:
Auditory Cortex; Electrophysiology; Auditory Evoked Potentials

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