Atención de enfermería para pacientes en post-transplantación de células de madre hematopoyéticas: revisión integrativa

Rodrigues, Jéssica Alline Pereira; Lacerda, Maria Ribeiro; Galvão, Cristina Maria; Gomes, Ingrid Meireles; Meier, Marineli Joaquim; Caceres, Nayla Tamara de Godoi

Jéssica Alline Pereira Rodrigues Corresponding author: Jéssica Alline Pereira Rodrigues. E-mail: jessica.rodrigues@hc.ufpr.br

Universidade Federal do Paraná. Curitiba, Paraná, Brazil.

https://orcid.org/0000-0001-5157-9698

Maria Ribeiro Lacerda

Universidade Federal do Paraná. Curitiba, Paraná, Brazil.

https://orcid.org/0000-0002-5035-0434

Cristina Maria Galvão

Universidade de São Paulo. Ribeirão Preto, São Paulo, Brazil.

https://orcid.org/0000-0002-4141-7107

Ingrid Meireles Gomes

Universidade Federal do Paraná. Curitiba, Paraná, Brazil.

https://orcid.org/0000-0002-2174-6421

Marineli Joaquim Meier

Universidade Federal do Paraná. Curitiba, Paraná, Brazil.

https://orcid.org/0000-0001-7350-1568

Nayla Tamara de Godoi Caceres

Universidade Federal do Paraná. Curitiba, Paraná, Brazil.

https://orcid.org/0000-0001-5658-3119

Corresponding author: Jéssica Alline Pereira Rodrigues. E-mail: jessica.rodrigues@hc.ufpr.br

EDITOR IN CHIEF: Dulce Barbosa

ASSOCIATE EDITOR: Marcia Magro

Database/Library	Search strategy
PubMed	("Hematopoietic Stem Cell Transplantation" OR "Stem Cell Transplantation, Hematopoietic" OR "Transplantation, Hematopoietic Stem Cell" OR "Bone Marrow Transplantation" OR "Grafting, Bone Marrow" OR "Bone Marrow Grafting" OR "Transplantation, Bone Marrow" OR "Bone Marrow Cell Transplantation" OR "Transplantation, Bone Marrow Cell" OR "Peripheral Blood Stem Cell Transplantation" OR "Peripheral Stem Cell Transplantation" OR "Stem Cell Transplantation, Peripheral" OR "Transplantation, Peripheral Stem Cell" ) AND ( "Nursing Care" OR "Care, Nursing" OR "Management, Nursing Care" OR "Nursing Care Management" OR "professional practice" OR "Practice, Professional" OR "Professional Practices" OR "Nursing, Practical" OR "Practical Nursing" OR "Nursings, Practical" OR "Practical Nursings" OR "Practice Patterns, Nurses'" OR "Nurses' Practice Patterns" OR "Nurse's Practice Patterns" OR "Nurse Practice Patterns" OR "Practice Pattern, Nurse's" OR "Practice Patterns, Nurse's" OR "Nurse-Led Clinics" OR "Clinic, Nurse-Led" OR "Clinics, Nurse-Led" OR "Nurse Led Clinics" OR "Nurse-Led Clinic" OR "Patient Care Planning" OR "Care Planning, Patient" OR "Planning, Patient Care" OR "Nursing Care Plans" OR "Care Plan, Nursing" OR "Care Plans, Nursing" OR "Nursing Care Plan" OR "Plan, Nursing Care" OR "Plans, Nursing Care" OR "Goals of Care" OR "Care Goal" OR "Care Goals" OR "Nursing Assessment" OR "Assessment, Nursing" OR "Assessments, Nursing" OR "Nursing Assessments" OR "Protocols, Nursing" OR "Nursing Protocol" OR "Protocol, Nursing" OR "Nursing Protocols")
Nursing VHL^* * Nursing VHL - Virtual Health Library;
CINAHL^† † CINAHL - Cumulative Index to Nursing & Allied Health Literature.
Web of Science
Scopus

Author(s)	Year/country	Type of study	Intervention/focus	Clinical question/level of evidence
Agulnik et al.⁽¹¹11 Agulnik A, Forbes PW, Stenquist N, Rodriguez-Galindo C, Kleinman M. Validation of a Pediatric Early Warning Score in hospitalized pediatric oncology and hematopoietic stem cell transplant patients. Pediatr Crit Care Med. 2016;17(4):146-53. https://doi.org/10.1097/PCC.0000000000000662 https://doi.org/10.1097/PCC.000000000000... ⁾	2016/ United States of America	Case-control study, comparative N=110 (transfers) N=220 (control)	Ability of the Pediatric Early Warning Score to predict unplanned transfer of patients to the Pediatric Intensive Care Unit.	Intervention/ treatment or diagnosis/diagnostic test/IV*
Araujo et al.⁽¹²12 Araujo DD, Rodrigues AB, Oliveira PP, Silva LS, Vecchia BP, Silveira EAA. Nursing diagnoses and interventions for patients with graft-versus-host disease submitted to hematopoietic stem cell transplantation. Cogitare Enferm [Internet]. 2015 [cited 2019 Sept 7];20(2):305-13. Available from: http://docs.bvsalud.org/biblioref/2016/08/1262/40340-157233-1-pb.pdf http://docs.bvsalud.org/biblioref/2016/0... ⁾	2015/ Brazil	Descriptive-exploratory, quantitative study n=30	Main diagnoses and nursing interventions for patients with graft-versus-host disease.	Prognosis/ prediction or etiology/IV†
Bergkvist et al.⁽¹³13 Bergkvist K, Larsen J, Johansson UB, Mattsson J, Svahn BM. Hospital care or home care after allogeneic hematopoietic stem cell transplantation - patients´ experiences of care and support. Eur J Oncol Nurs. 2013;17(4):389-95. https://doi.org/10.1016/j.ejon.2012.12.004 https://doi.org/10.1016/j.ejon.2012.12.0... ⁾	2013/ Sweden	Quasi-experimental study, control group not equivalent n=41	Satisfaction and experiences of care and support to patients during the acute phase after transplantation, when treated in the hospital or at home.	Intervention/ treatment or diagnosis/diagnostic test/III‡
Cater et al.⁽¹⁴14 Cater DT, Tori AJ, Moser EAS, Rowan CM. Modification and assessment of the bedside pediatric early warning score in the pediatric allogeneic hematopoietic cell transplant population. Pediatr Crit Care Med. 2018;19(5):483-8. https://doi.org/10.1097/PCC.0000000000001521 https://doi.org/10.1097/PCC.000000000000... ⁾	2018/ United States of America	Retrospective, single-center cohort study N=102	Validity of the Pediatric Early Warning Score in identifying patients who require critical intervention.	Prognosis/ prediction or etiology/II §
Cooke et al.⁽¹⁵15 Cooke L, Grant M, Gemmill R. Discharge needs of allogeneic transplantation recipientes. Clin J Oncol Nurs. 2012;16(4):142-9. https://doi.org/10.1188/12.CJON.E142-E149 https://doi.org/10.1188/12.CJON.E142-E14... ⁾	2012/ United States of America	Qualitative study N=141	Discussion of topics (diet, physical symptoms, emotional issues) that arose from spontaneous concerns of patients after teaching intervention.	Meaning/II\|\|
Cooke et al.⁽¹⁶16 Cooke LD, Gemmill R, Grant ML. Creating a palliative educational session for hematopoietic stem cell transplantation recipients at relapse. Clin J Oncol Nurs. 2011;15(4):411-7. https://doi.org/10.1188/11.CJON.411-417 https://doi.org/10.1188/11.CJON.411-417... ⁾	2011/ United States of America	Quasi-experimental study (no control group) N=4	Application of the content principles of End-of-life Nursing Education Consortium.	Intervention/ treatment or diagnosis/diagnostic test/III‡
Ferreira et al.⁽¹⁷17 Ferreira M, Nascimento LC, Braga FTMM, Silva-Rodrigues FM. Nurses´ competences in the critical care of children undergoing hematopoietic stem cell transplantation. Rev Eletrôn Enferm. 2017;19. https://doi.org/10.5216/ree.v19.43604 https://doi.org/10.5216/ree.v19.43604... ⁾	2017/ Brazil	Descriptive, qualitative study N=9	Nurses' experiences on competencies necessary for patient care.	Meaning/II\|\|
Gori et al.⁽¹⁸18 Gori E, Callea E, Alberani F, Orlando L. Microbial monitoring and methods of sample collection: a GITMO survey. Ecancer Med Sci. 2014;8:421. https://doi.org/10.3332/ecancer.2014.421 https://doi.org/10.3332/ecancer.2014.421... ⁾	2014/ Italy	Descriptive study N=48 centers	Application of Evidence-Based Practice to improve clinical practice.	Prognosis/ prediction or etiology/IV†
Kirsch et al.⁽¹⁹19 Kirsch M, Berben L, Johansson E, Calza S, Eeltink C, Stringer J, et al. Nurses' practice patterns in relation to adherence-enhancing interventions in stem cell transplant care: a survey from the Nurses Group of the European Group for Blood and Marrow Transplantation. Eur J Cancer Care (Engl). 2014;23(5):607-15. https://doi.org/10.1111/ecc.12172 https://doi.org/10.1111/ecc.12172... ⁾	2014/ Switzerland	Descriptive study N=143	Practice patterns of assessment/screening methods and interventions used to improve medication adherence.	Prognosis/ prediction or etiology/IV†
Lima et al.⁽²⁰20 Lima K, Bernardino E. Nursing care in a hematopoietic stem cells transplantation unit. Texto & Contexto Enferm. 2014;23(4):845-53. https://doi.org/10.1590/0104-07072014000440013 https://doi.org/10.1590/0104-07072014000... ⁾	2014/ Brazil	Descriptive, qualitative study N=12	Nurses' care activities.	Meaning/II\|\|
Lu et al.⁽²¹21 Lu DF, Hart LK, Lutgendorf SK, Oh H, Silverman M. Effects of healing touch and relaxation therapy on adult patients undergoing hematopoietic stem cell transplant: a feasibility pilot study. Cancer Nurs. 2016;39(3):1-11. https://doi.org/10.1097/NCC.0000000000000272 https://doi.org/10.1097/NCC.000000000000... ⁾	2016/ United States of America	Randomized study with two groups N=13 (intervention) N=13 (control)	Feasibility of the use of therapies similar to relaxation and relaxation therapy.	Intervention/ treatment or diagnosis/diagnostic test/II ¶
Meseguer-Liza et al.⁽²²22 Meseguer-Liza C, Caravaca-Hernández A, Solano-Antolinos J, López-Martínez S, Meseguer-Sánches, Sánches-Martínez C, et al. Prospective study of tympanic temperature in patients undergoing haemopoietic transplant. Enferm Clin. 2010;20(3):147-52. https://doi.org/10.1016/j.enfcli.2010.01.008 https://doi.org/10.1016/j.enfcli.2010.01... ⁾	2010/ Spain	Prospective descriptive study N=10	Reliability of the new fever diagnostic method.	Prognosis/ prediction or etiology/IV†
Montgomery et al.⁽²³23 Montgomery K, Belongia M, Schulta C, Mulberry MH, Nugent ML, Simpson PM. Health Care Providers' Perceptions of Nutrition Support in Pediatric Oncology and Hematopoietic Stem Cell Transplant Patients. J Pediatr Oncol Nurs. 2016;33(4):265-72. https://doi.org/10.1177/1043454215616604 https://doi.org/10.1177/1043454215616604... ⁾	2016/ United States of America	Cross-sectional descriptive study N=130	Description of perceptions of health care providers in relation to enteral and parenteral nutrition.	Prognosis/ prediction or etiology/IV†
Rodrigues et al.⁽²⁴24 Rodrigues C, Pinto C, Pereira F. A pessoa submetida a transplante de medula óssea: estudo exploratório sobre os padrões de documentação de cuidados de enfermagem. Onco News [Internet]. 2013 [cited 2019 Sept 8];22:17-22. Available from: https://www.aeop.pt/ficheiros/394382b2324b245084cfa33d4d0f6f78.pdf https://www.aeop.pt/ficheiros/394382b232... ⁾	2013/ Portugal	Exploratory-descriptive, quantitative, retrospective study N=122 (hospitalizations)	Profile of patients submitted to HSCT and identification of the standard of care documented by nurses.	Prognosis/ prediction or etiology/IV†
Rodrigues et al.⁽²⁵25 Rodrigues JAP, Lacerda MR, Gomes IM, Paes MR, Ribeiro RP, Mercês NNA. Research contributions for the nursing care in pediatric transplantation of hematopoietic stem cells. Rev Pesqui Cuid Fundam. 2018;10(4):964-70. https://doi.org/10.9789/2175-5361.2018.v10i4.964-970 https://doi.org/10.9789/2175-5361.2018.v... ⁾	2018/ Brazil	Quantitative, retrospective, cross-sectional study N=138	Nursing care for children in post-HSCT.	Prognosis/ prediction or etiology/IV†
Silva et al.⁽²⁶26 Silva JB, Póvoa VCO, Lima MHM, Oliveira HC, Padilha KG, Secoli SR. Nursing workload in hematopoietic stem cell transplantation: a cohort study. Rev Esc Enferm USP. 2015;49(Esp):92-8. https://doi.org/10.1590/S0080-623420150000700014 https://doi.org/10.1590/S0080-6234201500... ⁾	2015/ Brazil	Prospective cohort study N=62	Nursing workload	Prognosis/ prediction or etiology/II §
Valizadeh et al.⁽²⁷27 Valizadeh L, Zamanzadeh V, Sayadi L, Taleghani F, Howard AF, Jeddian A. Truth-telling and hematopoietic stem cell transplantation: Iranian nurses' experiences. Nurs Ethics. 2014;21(5):518-29. https://doi.org/10.1177/0969733013511359 https://doi.org/10.1177/0969733013511359... ⁾	2014/ Iran	Qualitative study N=18	Strategies used by nurses to communicate bad news.	Meaning/II\|\|
Vasquenza et al.⁽²⁸28 Vasquenza K, Ruble K, Chen A, Billett C, Kozlowski L, Atwater S, et al. Pain Management for Children during Bone Marrow and Stem Cell Transplantation. Pain Manag Nurs. 2015;16(3):156-62. https://doi.org/10.1016/j.pmn.2014.05.005 https://doi.org/10.1016/j.pmn.2014.05.00... ⁾	2015/ United States of America	Descriptive study N=51	Pain control practices and use of patient-controlled analgesia.	Prognosis/ prediction or etiology/IV†
Zamanzadeh et al.⁽²⁹29 Zamanzadeh V, Valizadeh L, Sayadi L, Taleghani F, Howard F, Jeddian A. Emotional labour of caring for hematopoietic stem cell transplantation patients: Iranian nurses' experiences. Asian Nurs Res. 2013;7(2):91-7. https://doi.org/10.1016/j.anr.2013.04.004 https://doi.org/10.1016/j.anr.2013.04.00... ⁾	2013/ Iran	Qualitative content analysis N=18	Emotional work experienced by nurses.	Meaning/II\|\|

Author (s)	Year/country	Type of study	Intervention/focus	Clinical question/level of evidence
Balian et al.⁽³⁰30 Balian C, Garcia M, Ward J. A retrospective analysis of bloodstream infections in pediatric allogeneic stem cell transplant recipients: the role of central venous catheters and mucosal barrier injury. J Pediatr Oncol Nurs. 2018;35(3):210-7. https://doi.org/10.1177/1043454218762706 https://doi.org/10.1177/1043454218762706... ⁾	2018/ United States of America	Retrospective cohort study N=78	Incidence of bloodstream infection associated with mucosal barrier injury and the relationship between fecal organisms.	Prognosis/ prediction or etiology/II*
Barrell et al.⁽³¹31 Barrell C, Covington L, Bathia M, Robison J, Patel S, Jacobson JS, et al. Preventive strategies for central line-associated bloodstream infections in pediatric hematopoietic stem cell transplant recipients. Am J Infect Control. 2012;40(5):434-9. https://doi.org/10.1016/j.ajic.2011.06.002 https://doi.org/10.1016/j.ajic.2011.06.0... ⁾	2012/ United States of America	Quasi-experimental study, time series model N=90	Catheter-associated bloodstream infection rates.	Intervention/ treatment or diagnosis/diagnostic test/III†
Bevans et al.⁽⁵5 Bevans M, Tierney DK, Bruch C, Burgunder M, Castro K, Ford R, et al. Hematopoietic stem cell transplantation nursing: a practice variation study. Oncol Nurs Forum. 2009;36(6):317-25. https://doi.org/10.1188/09.ONF.E317-E325 https://doi.org/10.1188/09.ONF.E317-E325... ⁾	2009/ United States of America	Cross-sectional study N=205	Variation in nursing practice with emphasis on infection control.	Prognosis/ prediction or etiology/IV‡
Daniels et al.⁽²2 Daniels P, Pate A, Flesch L, Teusink-Cross A, Matani H, Geiger A, et al. Improving time to antibiotic administration for bone marrow transplant patients with first fever. Pediatrics. 2018;141(1). https://doi.org/10.1542/peds.2017-1549 https://doi.org/10.1542/peds.2017-1549... ⁾	2018/ United States of America	Quasi-experimental study, time series model N=8	Mean time of antibiotic administration in patients admitted to the HSCT unit with initial fever.	Intervention/ treatment or diagnosis/diagnostic test/III†
Hou et al.⁽³²32 Hou C, Xu L, Chen H, Liu N, Jiang M, Wang G, et al. Intestinal aGVHD and infection after hematopoietic stem cell transplantation. Med Sci Monit. 2013;19:802-6. https://doi.org/10.12659/MSM.889408 https://doi.org/10.12659/MSM.889408... ⁾	2013/ China	Retrospective study N=44	Relationship between graft disease versus acute host and intestinal infection.	Prognosis/ prediction or etiology/IV‡
Livadiotti et al.⁽³³33 Livadiotti S, Milano GM, Serra A, Folgori L, Jenkner A, Castagnola E, et al. A survey on hematology-oncology pediatric AIEOP centers: prophylaxis, empirical therapy and nursing prevention procedures of infectious complications. Haematol. 2012;97(1):147-50. https://doi.org/10.3324/haematol.2011.048918 https://doi.org/10.3324/haematol.2011.04... ⁾	2012/ Italy	Nonexperimental study N=49 (oncology units)	Current practice of antimicrobial chemotherapy and chemoprophylaxis for febrile neutropenia.	Prognosis/ prediction or etiology/IV‡
Shelton et al.⁽³⁴34 Shelton BK, Stanik-Hutt J, Kane J, Jones RJ. Implementing the surviving sepsis campaign in an ambulatory clinic for patients with hematologic malignancies. Clin J Oncol Nurs. 2016;20(3):281-8. https://doi.org/10.1188/16.CJON.281-288 https://doi.org/10.1188/16.CJON.281-288... ⁾	2016/ United States of America	Quasi-experimental study, time series model N=40 (control) N=79 (intervention)	Time between the initial presentation of patients in the hospital, with possible sepsis (fever, neutropenia) until the first intervention.	Intervention/ treatment or diagnosis/diagnostic test/III†
Vokurka et al.⁽³⁵35 Vokurka S, Bystrická E, Svoboda T, Skoda G, Sever M, Mazur E, et al. The availability of HEPA-filtered rooms and the incidence of pneumonia in patients after haematopoietic stem cell transplantation (HSCT): results from a prospective, multicentre, eastern European study. J Clin Nurs. 2014;23(11-12):1648-52. https://doi.org/10.1111/jocn.12286 https://doi.org/10.1111/jocn.12286... ⁾	2014/ Czech republic	Observational, prospective, comparative, multicenter study N=689	High efficiency particulate air filtration and its impact on the incidence of pneumonia and mortality.	Prognosis/ prediction or etiology/IV‡
Andrade et al.⁽³⁶36 Andrade AM, Borges KS, Lima HO. Cost analysis and evaluation of covers for a central venous catheter insertion site in BMT. REME Rev Min Enferm. 2011;15(2):233-41. https://doi.org/S1415-27622011000200011 https://doi.org/S1415-27622011000200011... ⁾	2011/ Brazil	Retrospective, exploratory, descriptive study N=68	Use and cost of different types of covers in central venous catheter in relation to the frequency of exchange and frequency of infections.	Prognosis/ prediction or etiology/IV‡
Silveira et al.⁽³⁷37 Silveira RCCP, Braga FTMM, Garbin LM, Galvão CM. The use of polyurethane transparent film in indwelling central venous catheter. Rev Latino-Am Enfermagem. 2010;18(6):1212-20. https://doi.org/10.1590/S0104-11692010000600023 https://doi.org/10.1590/S0104-1169201000... ⁾	2010/ Brazil	Case series N=10	Frequency of infection, related to catheter, and skin toxicity, to the use of polyurethane dressing.	Prognosis/ prediction or etiology/IV‡
Flynn et al.⁽³⁸38 Flynn JM, Keogh SJ, Gavin NC. Sterile v aseptic non-touch technique for needle-less connector care on central venous access devices in a bone marrow transplant population: a comparative study. Eur J Oncol Nurs. 2015;19(6):694-700. https://doi.org/10.1016/j.ejon.2015.05.003 https://doi.org/10.1016/j.ejon.2015.05.0... ⁾	2015/ Australia	Comparative study of two groups without competing controls N=150	Assessment of change in practice on the connector without needle in a central catheter associated with the occurrence of infection.	Intervention/ treatment or diagnosis/diagnostic test/III†
Keeler⁽³⁹39 Keeler M. Central line practice in Canadian blood and marrow transplant. Can Oncol Nurs J. 2014;24(2):67-71. https://doi.org/10.5737/1181912x2426771 https://doi.org/10.5737/1181912x2426771... ⁾	2014/ United States of America	Non-experimental study N=25 centers	Adhering to the recommended guidelines for central catheter management.	Prognosis/ prediction or etiology/IV‡
Carvalho et al.⁽⁴⁰40 Carvalho ALG, Rosa LM. Dressing of central venous catheter of short permanence: nursing care. J Nurs UFPE. 2014;8(7):1972-8. https://doi.org/10.5205/5941 https://doi.org/10.5205/5941... ⁾	2014/ Brazil	Documentary research N=3	Standardization of the central venous catheter dressing technique.	Prognosis/ prediction or etiology/IV‡
Yilmaz et al.⁽⁴¹41 Yilmaz MC, Aksoylar S, Erdogan D, Demirag B. Complications of central venous catheters in children undergoing hematopoietic stem cell transplantation in Turkey. J Pediatr Oncol Nurs. 2012;29(4):199-205. https://doi.org/10.1177/1043454212451366 https://doi.org/10.1177/1043454212451366... ⁾	2012/ Turkey	Prospective study N=114 (catheters)	Types, rates and risk factors for complications related to central catheters.	Prognosis/ prediction or etiology/IV‡
Bhatt et al.⁽⁴²42 Bhatt V, Vendrell N, Nau K, Crumb D, Roy V. Implementation of a standardized protocol for prevention and management of oral mucositis in patients undergoing hematopoietic cell transplantation. J Oncol Pharm Pract. 2010;16(3):195-204. https://doi.org/10.1177/1078155209348721 https://doi.org/10.1177/1078155209348721... ⁾	2010/ United States of America	Quasi-experimental study, time series model N=13 (control) N=12 (intervention)	Implementation of a standardized oral care protocol for the prevention and management of mucositis.	Intervention/ treatment or diagnosis/diagnostic test/III†
Braga et al.⁽⁴³43 Braga FT, Santos AC, Bueno PC, Silveira RC, Santos CB, Bastos JK, et al. Use of chamomilla recutita in the prevention and treatment of oral mucositis in patients undergoing hematopoietic stem cell transplantation: a randomized, controlled, phase II clinical trial. Cancer Nurs. 2015;38(4):322-9. https://doi.org/10.1097/NCC.0000000000000194 https://doi.org/10.1097/NCC.000000000000... ⁾	2015/ Brazil	Randomized clinical trial N=40	Chamomilla recutita dosage in mouthwash required to reduce incidence and intensity of mucositis.	Intervention/ treatment or diagnosis/diagnostic test/II §
Leppla et al.⁽⁴⁴44 Leppla L, De Geest S, Fierz K, Deschler-Baier B, Koller A. An oral care self-management support protocol (OrCaSS) to reduce oral mucositis in hospitalized patients with acute myeloid leukemia and allogeneic hematopoietic stem cell transplantation: a randomized controlled pilot study. Support Care Cancer. 2016;24(2):773-82. https://doi.org/10.1007/s00520-015-2843-1 https://doi.org/10.1007/s00520-015-2843-... ⁾	2016/ Switzerland	Randomized clinical trial (pilot) N=18	Development of a self-management support protocol for oral care in the prevention of mucositis.	Intervention/ Treatment or Diagnosis/Diagnostic Test/II §
Treister et al.⁽⁴⁵45 Treister NS, London WB, Guo D, Malsch M, Verrill K, Brewer J, et al. A feasibility study evaluating extraoral photobiomodulation therapy for prevention of mucositis in pediatric hematopoietic cell transplantation. Photomed Laser Surg. 2016;34(4):178-84. https://doi.org/10.1089/pho.2015.4021 https://doi.org/10.1089/pho.2015.4021... ⁾	2016/ United States of America	Quasi-experimental study N=13	Viability of low-level light therapy or combined photobiomodulation therapy for the prevention of mucositis.	Intervention/ treatment or diagnosis/diagnostic test/III†

Author(s)	Year/country	Type of study	Intervention/focus	Clinical question/level of evidence
Barban et al.⁽⁴⁶46 Barban A, Coracin FL, Musqueira PT, Barban A, Ruiz LP, Ruiz MA, et al. Analysis of the feasibility of early hospital discharge after autologous hematopoietic stem cell transplantation and the implications to nursing care. Rev Bras Hematol Hemoter. 2014;36(4):264-8. https://doi.org/10.1016/j.bjhh.2014.05.003 https://doi.org/10.1016/j.bjhh.2014.05.0... ⁾	2014/ Brazil	Retrospective, quantitative, descriptive, cross-sectional study N=110	Results of hospital discharge as a viable alternative in treatment.	Prognosis/ prediction or etiology/ IV*
Best et al.⁽⁴⁷47 Best D, Osterkamp E, Demmel K, Kiniyalocts S, Mock S, Mulligan K, et al. Increasing activities of daily living is as easy as 1-2-3. J Pediatr Oncol Nurs. 2016;33(5):345-52. https://doi.org/10.1177/1043454215616607 https://doi.org/10.1177/1043454215616607... ⁾	2016/ United States of America	Quasi-experimental study, time series model N=100	Creation and implementation of standardized process of compliance with activities of daily living.	Intervention/ treatment or diagnosis/diagnostic test/III†
Castro et al.⁽⁴⁸48 Castro EAB, Andrade AM, Santos KB, Soares TC, Esterci LT. Self-care after autologous bone marrow transplantation within the nursing care process. Rev Rene [Internet]. 2012 [cited 2019 Sept 7];13(5):1152-62. Available from: http://periodicos.ufc.br/rene/article/view/4126/3213 http://periodicos.ufc.br/rene/article/vi... ⁾	2012/ Brazil	Qualitative study n=7	The influence of orientations provided at discharge on self-care after transplantation.	Meaning/II‡
Schmidt et al.⁽⁴⁹49 Schmidt H, Boese S, Bauer A, Landenberger M, Lau A, Stoll O, et al. Interdisciplinary care programme to improve self-management for cancer patients undergoing stem cell transplantation: a prospective non-randomised intervention study. Eur J Cancer Care (Engl). 2017;26(4). https://doi.org/10.1111/ecc.12458 https://doi.org/10.1111/ecc.12458... ⁾	2017/ Germany	Prospective intervention study (non-randomized) N=79	Intervention to improve patients' self-management skills regarding activation and relaxation, prevention of oral mucositis and malnutrition.	Intervention/ treatment or diagnosis/diagnostic test/III†
Thomson et al.⁽⁵⁰50 Thomson B, Gorospe G, Cooke L, Giesie P, Johnson S. Transitions of care: a hematopoietic stem cell transplantation nursing education project across the trajectory. Clin J Oncol Nurs. 2015;19(4):74-9. https://doi.org/10.1188/15.CJON.E74-E79 https://doi.org/10.1188/15.CJON.E74-E79... ⁾	2015/ United States of America	Quasi-experimental study N=22	Minimization of the variability of teaching content and improvement of nurses' competence.	Intervention/ treatment or diagnosis/diagnostic test/III†

[1] Corresponding author: Jéssica Alline Pereira Rodrigues. E-mail: jessica.rodrigues@hc.ufpr.br

Brasil

Brasil

Atención de enfermería para pacientes en post-transplantación de células de madre hematopoyéticas: revisión integrativa

RESUMEN

Objetivos:

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