A1(1717. Grauhan O, Navasardyan A, Hofmann M, Müller P, Stein J, Hetzer R. Prevention of poststernotomy wound infections in obese patients by negative pressure wound therapy. J Thorac Cardiovasc Surg. 2013;145(5):1387-92. DOI: http://dx.doi.org/10.1016/j.jtcvs.2012.09.040
http://dx.doi.org/10.1016/j.jtcvs.2012.0...
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Prevention of post sternotomy wound infections in obese patients by negative pressure wound therapy |
Germany 2013 |
Prospective case-control observational |
Case – negative pressure wound therapy (Prevena™ – Incision Management System) Control – conventional sterile dressings |
Infection Case – Three of 75 (4%) patients presented infection Control – 12 of 75 (16%) (OR= 4.57; CI95%= 1.23-16.94, p = 0.026) |
NOS
6 |
A2(1818. Bakri M, Nagem H, Sessler D, Mahboobi R, Dalton J, Akça O, et al. Transdermal oxygen does not improve sternal wound oxygenation in patients recovering from cardiac surgery. Anesth Analg. 2008;106(6):1619-26.)
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Transdermal Oxygen Does Not Improve Sternal Wound Oxygenation in Patients Recovering from Cardiac Surgery |
United States, 2008 |
Randomized |
Intervention – transdermal continuous oxygen therapy (EpiFLO® oxygen generators) Control – transdermal continuous oxygen therapy (innactive EpiFLO® oxygen generators) |
Reduction of infection Increasing FiO2 from 30% to 50% increased arterial oxygen from 99 (84 –116) to 149 (128 –174) mmHg (p < 0.001)and sternal wound tissue oxygen tension from 23 (16 –33) to 27 (19 –38) mmHg (p < 0.001) Local oxygen delivery did not improve tissue oxygenation: 24 (14-41) vs. 25 (16-41) mmHg (p=0.88) |
JADAD
5 |
A3(1919. Huckfeldt R, Redmond C, Mikkelson D, Finley P, Lowe C, Robertson J. A clinical trial to investigate the effect of silver nylon dressings on mediastinitis rates in postoperative cardiac sternotomy. Ostomy Wound Manage. 2008;54(10):36-41.)
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A Clinical Trial to Investigate the Effect of Silver Nylon Dressings on Mediastinitis Rates in Postoperative Cardiac Sternotomy |
United States, 2008 |
Retrospective/prospective study, observational |
Case – silver nylon dressing (Silverlon® Island Dressing) Control – standard gauze dressings |
Mediastinitis Case – no patient (0%) developed mediastinitis Control – 13 patients (1.1%) developed mediastinitis (χ2 = 3.88, p<0.05). |
NOS
6 |
A4(2020. Segers P, de Jong AP, Spanjaard L, Ubbink DT, de Mol BA. Randomized clinical trial comparing two options for postoperative incisional care to prevent poststernotomy surgical site infections. Wound Repair Regen. 2007;15(2):192-6.)
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Randomized clinical trial comparing two options for postoperative incisional care to prevent poststernotomy surgical site infections |
The Netherlands, 2007 |
Randomized trial |
Intervention – water and air impermeable adhesive drape (Opsite™). Control – water- and air-permeable absorbent dressing (Hansapor™). |
Surgical site infection There was no significant difference in the incidence of sternal surgical site infection between groups (2.6 vs. 3.3%) |
JADAD
3 |
A5(2121. Colli A, Camara ML. First experience with a new negative pressure incision management system on surgical incisions after cardiac surgery in high risk patients. J Cardiothorac Surg [Internet]. 2011 [cited 2017 Jan 21];6:160. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305521
https://www.ncbi.nlm.nih.gov/pmc/article...
)
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First experience with a new negative pressure incision management system on surgical incisions after cardiac surgery in high risk patients |
Spain, 2011 |
Prospective cohort, observational |
Negative pressure wound therapy (Prevena™ – Incision Management System) The dressing contains ionic silver (0.019%) |
Complete wound healing Wounds and surrounding skin showed complete wound healing with the absence of skin lesions due to the negative pressure after removal of the Prevena™ dressing. |
NOS
3 |
A6(2222. Grauhan O, Navasardyan A, Tutkun B, Hennig F, Müller P, Hummel M, et al. Effect of surgical incision management on wound infections in a poststernotomy patient population. Int Wound J. 2014;11 Suppl 1:6-9.)
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Effect of surgical incision management on wound infections in a post sternotomy patient population |
Germany, 2014 |
Prospective cohort, observational |
Control – conventional sterile wound tape dressings Intervention – negative pressure wound therapy (Prevena™ – Incision Management System) |
Wound infection within 30 days. Significantly lower infection rate than control group: 1.3% (3 patients) vs. 3,4% (119 patients), respectively (OR = 2.74; p<0.05) |
NOS
7 |
A7(2323. Atkins B, Wooten M, Kistler J, Hurley K, Hughes G, Wolfe W. Does negative pressure wound therapy have a role in preventing poststernotomy wound complications? Surg Innov. 2009;16(2):140-6.)
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Does Negative Pressure Wound Therapy Have a Role in Preventing Post sternotomy Wound Complications? |
United States, 2009 |
Retrospective cohort, observational |
Negative pressure wound therapy |
Infection No cases of sternal wound infection were found |
NOS
4 |