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Prevalence of infection in kidney transplantation from living versus deceased donor: systematic review and meta-analysis

Prevalencia de infección en trasplante renal de donante vivo versus fallecido: revisión sistemática y metanálisis

OBJECTIVE

To verify if the type of donor is a risk factor for infection in kidney transplant recipients.

METHODS

Systematic Review of Literature with Meta-analysis with searches conducted in the databases MEDLINE, LILACS, Embase, Cochrane, Web of Science, SciELO and CINAHL.

RESULTS

We selected 198 studies and included four observational studies describing infections among patients distinguishing the type of donor. Through meta-analysis, it was shown that in patients undergoing deceased donor transplant, the outcome infection was 2.65 higher, than those who received an organ from a living donor.

CONCLUSION

The study showed that deceased kidney donor recipients are at an increased risk for developing infections and so the need for establishing and enforcing protocols from proper management of ischemic time to the prevention and control of infection in this population emerges.

Kidney Transplantation; Tissue Donors; Living Donors; Infection; Review


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E-mail: reeusp@usp.br