Objective:
to investigate the association between central line-associated bloodstream infections and clinical and care variables of intensive care unit patients with COVID-19 hospitalized at a reference public health institution.
Method:
a case-control study.
Results:
the study sample consisted of 70 patients diagnosed with central line-associated bloodstream infections (case group) and 70 non-infected patients (control group). Most patients were male, with mean age of 57.93±13.93 years old and provided with a double lumen catheter. Median time of central line-associated bloodstream infections onset was 11 (8-18) days. Longer time on mechanical ventilation ( P =0.014; OR: 1.79; 95% CI: 0.91-3.51) and prone position ( P =0.017; OR: 2.41; 95% CI: 1.22-4.81) were associated with central line-associated bloodstream infections onset.
Conclusion:
longer time on invasive mechanical ventilation and prone position contributed to central line-associated bloodstream infections onset in COVID-19 patients.
Descriptors:
COVID-19; Central Venous Catheterization; Sepsis; Prone Position; Mechanical Ventilation; ICU
Highlights:
(1) During ICU hospitalization, the central venous catheter (CVC) is essential.
(2) Patients with COVID-19 in the ICU should be observed for infection.
(3) Longer time on invasive mechanical ventilation and prone are related factors.