Acessibilidade / Reportar erro

Evaluation of the cholesterol-lowering efect of high-fiber dehydrated soup in rats

The effect of 4 high fiber dietary formulas on reducing blood cholesterol levels in rats was evaluated in the present study. The products were formulated with defatted soy flour, oat bran, dehydrated onion, soy fiber and spices. Two of them contained black beans, FP(+) or FP(-), at 40 or 30%, respectively. The other two contained red beans, FV(+) or FV(-), at the same levels. Six groups of 8 male rats, with initial body weight of about 200g, were used. The Standard group received a basal diet. The Control group received a similar diet, but it was added 1% of cholesterol and 0.1% of cholic acid. The other diets were similar to the Control one, substituted for the formulas FV(+), FP(+), FV(-) and FP(-) to provide 7.4% of total dietary fiber. Rats fed on Control diet showed a significant increase in their blood cholesterol levels, liver weight and fecal and liver cholesterol and total lipid, in relation to the Standard group. There was no significant difference among the diets FV(+), FP(+), FV(-) and FP(-) in terms of blood levels of cholesterol, triglycerides and glucose, liver weight, liver total lipids, fecal weight and moisture and the output of nitrogen. All the formulas reduced blood cholesterol levels by 29%, HDL-cholesterol by 34%, liver weigth by 11.7% and liver cholesterol by 9%, in comparison with the Control diet. The diets containing red beans showed higher reductions of cholesterol in the rat liver and higheroutput of total lipids and cholesterol than the black bean diets.

dietary fiber; cholesterol; cereals


Pontifícia Universidade Católica de Campinas Núcleo de Editoração SBI - Campus II , Av. John Boyd Dunlop, s/n. - Prédio de Odontologia, 13059-900 Campinas - SP Brasil, Tel./Fax: +55 19 3343-6875 - Campinas - SP - Brazil
E-mail: sbi.submissionrn@puc-campinas.edu.br