menu menu_open
Brasil
home Sumário navigate_before Anterior Atual Seguinte navigate_next
home Sumário
Original Article • Rev. Odontol. UNESP 51 • 2022 • https://doi.org/10.1590/1807-2577.00622 linkcopy

Open-access Cariogenic and erosive potential of pediatric medicines and vitamin supplements

Potencial cariogênico e erosivo de medicamentos e suplementos vitamínicos pediátricos

AuthorshipSCIMAGO INSTITUTIONS RANKINGS

    Abstract

    Introduction  Pharmaceutical pediatric formulations with low in pH and high in total titratable acidicity used frequently and over long periods of time, have the potential to produce erosive lesions in teeth. On the other hand, high concentration of sucrose, the nocturnal use and the lack of hygiene after its administration, are some factors that can contribute to the cariogenic potential of these formulations.

    Objective  To evaluate in vitro the cariogenic and erosive potential of medicines and liquid vitamins and mineral supplements for pediatric use.

    Material and method  Medicines (n=41) and liquid vitamins and mineral supplements (n=12) childish were selected and analyzed for their physicochemical properties, pH, total titratable acidity (TTA) and total soluble solids concentration (TSS/°Brix). The package inserts and labels were analyzed to identify the composition regarding the content of sugars and acidulants, in addition to the side effects related to salivary flow.

    Result  The pH analysis indicated that there was greater variation in the observed averages in the medication group. As for the TTA at pH 5.5, supplements and medicines groups showed significant variation between the means found (p<0.05). The TTA results at pH 7.0 showed that the highest mean found was in the class of antihistamines and the lowest in the class of drugs that contain the association of antitussives and antihistamines. The analyses TSS demonstrated that across all drug classes and supplements the amount of TSS varied significantly (p<0.05) in all classes of medicines and supplements.

    Conclusion  Most medicines and pediatric liquid vitamin and mineral supplements demonstrated significantly different behaviors within the group itself regarding the variables analyzed that constitute risk factors for the development of dental caries and erosion.

    Descriptors:  Dental caries; tooth erosion; pharmaceutical preparations

    vertical_align_top file_download show_chart
    location_on
    Universidade Estadual Paulista Júlio de Mesquita Filho Rua Humaitá, 1680 - Caixa Postal 331, 14801-903 Araraquara,São Paulo,SP, Tel.: (55 16) 3301-6376, Fax: (55 16) 3301-6433 - Araraquara - SP - Brazil
    E-mail: adriana@foar.unesp.br
    rss_feed Acompanhe os números deste periódico no seu leitor de RSS
    Acessibilidade / Reportar erro