Open-access Dipyrone versus acetaminophen in the control of postoperative pain

rounesp Revista de Odontologia da UNESP Rev. odontol. UNESP 0101-1774 1807-2577 Universidade Estadual Paulista Júlio de Mesquita Filho Araraquara, SP, Brazil INTRODUCTION: The pain is defined as an unpleasant experience, and control of postoperative pain a great challenge in healthcare. OBJECTIVE: To compare the efficacy of Dipyrone and acetaminophen in postoperative pain after third molar surgery. MATERIAL AND METHOD: Thirty patients of the Discipline of Surgery of School of Dentistry of Araçatuba - UNESP, that needed to extract their third included molars, were selected. Among these, 15 received Dipyrone (group I) and the other received acetaminophen (group II) in the postoperative. All patients were treated pre-operatively with dexamethasone 4 mg and amoxycillin 1 g, one hour before surgery. Pain intensity was evaluated by a visual analogue scale by forty eight hours postoperative period and in intervals of six hours. The exclusion criteria were: presence of systemic disorders, drugs hypersensitivity, pregnant, lactic and local contraindications. The scores obtained were submitted to the Mann-Whitney test (p < 0,05) for comparison of the pain intensity in the 6 hours intervals, in the initial 24 hours, in the last 24 hours and in the total period of 48 hours. RESULT: There was no statistical difference among the analgesics in the 6 hours intervals, however, in the last 24 hours and in the total period of 48 hours, the group I presented smaller medium values, significant statistically, when compared to group II. CONCLUSION: The analgesic efficacy of dipyrone was superior to paracetamol. 1 1. Andrade ED. Terapêutica medicamentosa em odontologia. 2ª ed. São Paulo: Artes Médicas; 2000. Terapêutica medicamentosa em odontologia 2000 Andrade ED 2 2. Sener M, Yilmazer C, Yilmaz I, Bozdogan N, Ozer C, Donmez A. 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