Amin et al, 1980(28)
|
Study 1: Cross- sectional Study 2: Longitudinal |
USA |
Study 1: 68 preterm infants (GA 28–36wks.), 18 term infants, 50 normal children. Study 2: 8 preterm infants with severe respiratory insufficiency. Assessment until the 6th wk of age. |
PN and F |
Lockitch et al, 1989(21)
|
Prospective observational longitudinal |
Canada |
Baseline: 56 healthy term newborns and 39 LBW infants with a mean (SD) BW of 1940±257g and 35 VLBW infants of 1064±264g with <37wks. of gestation. Assessment until the 7th wk of life in 16 preterm infants. |
PN (without Se) with or without oral intake. |
Huston et al, 1991(47)
|
Prospective Randomized Clinical Trial |
USA |
20 preterm infants (BW<1000 g). The mean (SD) GA in G1=26.7±1.5 and G2=26.5±1.2 wks. Assessment until the 60th day. |
PN and EN. G1 (n = 10; 1.34µg/kg/day of selenious acid) and G2 (without Se). |
Smith et al, 1991(29)
|
Prospective Clinical Trial |
USA |
46 preterm infants (BW<1700 g). The mean GA was 29.3 weeks. Assessment until the 3th wk of life. |
BF (n=21; 24ng Se/mL), F (n=13; 7.8 ng Se/mL), and F (n=12; 34.8 ng Se/mL). |
Mask et al, 1993(27)
|
Cross-sectional |
USA |
13 preterm newborns (Mean (SD) BW and GA was 1869±449g and 33.5±1.8wks.), 15 term newborns and their mothers and 15 women who were not pregnant. |
(Not differentiated) |
Darlow et al, 1995(32)
|
Prospective observational longitudinal |
New Zealand |
79 preterm newborns with a mean (SD) GA of 28.3±2.5wks. And BW of 1164±254g. Assessment until the 28th day of life. |
PN (without Se), EN and BF or F. |
Daniels et al, 1996(18)
|
Prospective Randomized Clinical Trial |
Australia |
Preterm newborns (G1: 19 and G2: 19) healthy term newborns (RG=32). The mean (SD) BW and GA were 1171±38g and 29±0.3wks. Assessment until the 6th wk of life. |
G1:PN (without Se), G2:PN (3µg/kg/day of selenious acid) and RG (F and BF). |
Bogye et al, 1998(51)
|
Randomized Clinical Trial |
Hungary |
36 preterm newborns with VLBW. BW of 975±122g and GA 27±1wk. Supplementation for 14 days. |
G1 (n=18): (nasogastric EN by drip) with 4.8mg yeast (5µg of Se) G2 (n=18): not supplied |
Bogye et al, 1998(38)
|
Randomized Clinical Trial |
Hungary |
28 preterm newborns with birth weight and GA of 962±129g and 27±1wk. Supplementation for 14 days. |
G1 (n=14): (nasograstric EN by drip) with 4.8mg of yeast (5µg of Se). G2 (n=14): not supplied |
Merz et al, 1998(40)
|
Prospective |
Germany |
34 VLBW infants with GA and BW 28.6±2.5wks. and 1075±249g respectively. Assessment until 4th wk of life. |
Mainly PN and were not specifically supplied with Se. |
Klinger et al, 1999(39)
|
Cross-sectional |
Israel |
29 VLBW infants with mean (SD) age and weight 26±1.7wks and 809±129g |
Se: 2µg/kg/d selenious acid. |
Darlow et al, 2000(24) |
Double-blind placebo-controlled randomized Trial |
New Zealand |
534 infants with BW<1500g Assessment until 36wks of life. |
PN: 7µg/kg/d and F: 5µg/kg/day sodium selenite. |
Winterbourn et al, 2000(48) |
Randomized controlled Trial |
New Zealand |
173 newborns with weight <1500g. Assessment until 36wks of life. |
PN: 7µg/kg/d and F: 5µg/kg/day sodium selenite. |
Sievers et al, 2001(45)
|
Prospective observational longitudinal |
Germany |
16 preterm newborns (GA 25–32wk and BW 595–1495g), 14 term newborns with F and 17 term newborns with BF. Assessment until 1st year of life. |
BF, F and complementary feeding. |
Makhoul et al, 2004(8)
|
Cross-sectional |
Israel |
165 preterm newborns and term newborns (24–42wks.) and their mothers. |
(Not differentiated) |
Mentro et al, 2004(9)
|
Prospective observational longitudinal |
14 Caucasians, 3 Hispanics and 1 Asian-American |
18 preterm newborns with BW of 1013g (650–1370g) and risk of BPD. Mean GA was 27 weeks. Assessment until 4th week of life. |
BF, PN, EN and F. Mean ingestion of Se in the 1st wk was 0.82µg/kg/day and 1.7µg/kg/day in the 4th wk. |
Galinier et al, 2005(30)
|
Cross-sectional |
France |
248 preterm newborns and 262 term newborns. The mean GA and BW (SD) for preterm newborns was 32.4±2.52wks. and 1845±489g. |
(Not differentiated) |
Nassi et al, 2009(10) |
Prospective observational longitudinal |
Italy |
30 preterm infants with mean (SD) BW and GA of 1605±122 g and 34.5±0.5 wk. The control group included 30 term infants. Assessment until the 100th day of life. |
BF |