In a fatal dissease among wild herons (Casmerodius albus egretta), the authors isolated Salmonella typhimurium from tissues. The observations were made in the city of Rio de Janeiro and the infected fowls showed depression (Fig. 1 and 2). The principal gross lesions ocurred in the liver where hepatomegalia and miliary necrosis were observed (Fig. 3). The microscopic examination of the liver showed miliary necrosis centrally occupied by colonies of bacteria (Fig. 4 and 5). The authors isolated also Salmonella typhimurium from waterofa lake where the fowls had access every day. This is the first observation of infection by Salmonella typhimurium in herons (Casmerodius albus egretta) according the literature consulted.