Prevalence and antibiogram of methicillin resistant Staphylococcus aureus isolated from medical device-related infections; a retrospective study in Lahore, Pakistan

Abstract

INTRODUCTION:

With the advancement of medicine and surgery, various types of medical devices have become part of treatment strategies.

METHODS:

Identification and antimicrobial sensitivity testing were done according to CLSI guidelines following standard microbiological practices.

RESULTS:

Urinary catheter infections (31%) were most frequent followed by central venous catheter (18%) and orthopedic implants (15%). Methicillin resistant Staphylococcus aureus (MRSA) was a major cause of device-related infection after Escherichia coli (21%); other pathogens were Klebsiella pneumoniae (14%), Pseudomonas spp. (10%), Acinetobacter spp. (8%) and Candida species (7%). None of MRSA was resistant to vancomycin (MIC ≥16µg/mL). Resistance rates were 98% and 97% for ofloxacin and ciprofloxacin, respectively.

CONCLUSIONS

Escherichia coli and MRSA are major pathogens of medical device-related infections.

Keywords:
Prosthetic devices; MRSA; Escherichia coli; Vancomycin; Antibiogram