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Short Communication • Rev. Soc. Bras. Med. Trop. 51 (02) • Mar-Apr 2018 • https://doi.org/10.1590/0037-8682-0298-2017   copy

The role of the Xpert MTB/RIF assay among adolescents suspected of pulmonary tuberculosis in Rio de Janeiro, Brazil

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstract

INTRODUCTION

The teste rápido molecular para tuberculose (TRM-TB) was introduced in 2014 in Brazil for tuberculosis screening. However, its role in adolescents in Brazil has not been studied.

METHODS

A descriptive study of adolescents with suspected tuberculosis using National Laboratory software.

RESULTS

Of 852 (15.4%) suspected cases, 131 were positive by TRM-TB and 2% were resistant to rifampicin. Among TRM-TB-positive cases, 105 (91.4%) were culture-positive. Sixty-four of 96 samples were sensitive to rifampicin by TRM-TB; 11 were resistant to other drugs by drug sensitivity test (DST).

CONCLUSIONS

Among suspected cases, 16% were diagnosed by TRM-TB, of which 17% were drug-resistant by DST.

Keywords:
Tuberculosis; Adolescents; Polymerase chain reaction

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