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Short Communications • Rev. Soc. Bras. Med. Trop. 46 (2) • Mar-Apr 2013 • https://doi.org/10.1590/0037-8682-1060-2013   copy

Susceptibility to amphotericin B of Candida spp. strains isolated in Ceará, Northeastern Brazil

Authorship SCIMAGO INSTITUTIONS RANKINGS

Introduction

Amphotericin B (AMB) is an antifungal agent used extensively in clinical medicine, yet resistance remains low. This study aims to evaluate the susceptibility of Candida spp. against AMB.

Methods

For broth microdilution susceptibility testing, 77 strains of Candida spp. were selected (32 C. albicans, 33 C. tropicalis, and 12 C. parapsilosis). The strains were considered susceptible when they exhibited MIC≤1.0µg/ml.

Results

None of the strains showed an MIC greater than 0.25µg/ml.

Conclusions

Further works are necessary, with a higher number of strains, to assess the validity of the results used in this study.

Amphotericin B; Candida spp; Protocol M27-A3

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