An 85-year-old man presented to our hospital for the evaluation of dyspnea and cough. Diffuse tracheal papillomatosis was noted on computed tomography findings (Figure 1A and Figure 1B).
Chest computed tomography findings in the coronal (A) and air-specific reformat (B) views demonstrating diffuse tracheal papillomatosis (arrows).
Respiratory papillomatosis usually develops from persistent infection of the respiratory mucosal epithelium by human papillomavirus 6 or 11 strains. Approximately 5% of patients with laryngeal papillomatosis have involvement of the trachea, proximal bronchi, or both. Malignant transformation rarely occurs in cases of recurrent respiratory papillomatosis11. Zeleník K, Komínek P, Staníková L, Formánek M. Local Bevacizumab Treatment of Juvenile-Onset Respiratory Papillomatosis Might Induce Multiple Tracheal Pyogenic Granulomas. Laryngoscope. 2021;131(2):E518-E520.,22. Shai SE, Wang LL, Hung SC. Curing a Patient of Recurrent Tracheal Papillomatosis Using Laser Ablation and Adjuvant Radiotherapy. Ann Thorac Surg. 2020;110(2):e91-e93.. Tracheal papillomatosis should be kept in mind as a rare cause of cough and dyspnea.
REFERENCES
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1Zeleník K, Komínek P, Staníková L, Formánek M. Local Bevacizumab Treatment of Juvenile-Onset Respiratory Papillomatosis Might Induce Multiple Tracheal Pyogenic Granulomas. Laryngoscope. 2021;131(2):E518-E520.
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2Shai SE, Wang LL, Hung SC. Curing a Patient of Recurrent Tracheal Papillomatosis Using Laser Ablation and Adjuvant Radiotherapy. Ann Thorac Surg. 2020;110(2):e91-e93.
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Financial Support: The authors declare that the article content was composed in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Publication Dates
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Publication in this collection
25 July 2022 -
Date of issue
2022
History
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Received
17 Mar 2022 -
Accepted
19 May 2022