Nucci and Anaissie |
2007 |
Clinical Microbiology Reviews |
Infections by the Fusarium species are superficial in healthy patients, and these patients |
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tend to respond well to therapy. Disseminated fusariosis affects the |
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immunocompromised host and is often fatal. |
Katiyar and Edlind |
2009 |
Antimicrobials Agents and |
Genetic mutations in Fks sequences result in decreased sensitivity of the Fusarium sp., |
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Chemotherapy |
rendering it difficult to treat human fusariosis. |
Romani |
2011 |
Nature Reviews Immunology |
When the infective structures of Fusarium spp. reach the mucous membranes, the |
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innate cellular immune response of the host is activated, which includes dendritic cells, |
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macrophages, monocytes, neutrophils, and soluble mediators of the complement system. |
Guarro et al. |
2013 |
European Journal of Clinical |
Fusariosis is related to high mortality. Recovery from neutropenia remains the most important determinant of outcomes in such patients. |
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Microbiology & Infectious Diseases |
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Nucci et al. |
2014 |
Clinical Microbiology and |
Significant improvement in the results of invasive fusariosis in the last decade with |
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Infection |
changes in therapeutic practices, involving a decrease in the use of amphotericin B and |
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increase in the use of voriconazole and combination therapy. |
Spolti et al. |
2014 |
Plant Disease |
Epidemic of fusariosis in plants can be harmful to humans and animal health, since the |
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ingestion of cereals contaminated with mycotoxins can cause serious food poisoning. |
van Diepeningen et al. |
2014 |
Current Clinical Microbiology Reports |
The use of molecular techniques is recommended to identify Fusarium species that cause infections. |
Varon et al. |
2014 |
The Journal of Infection |
Skin lesions may be considered entry points for Fusarium spp. Infections, especially in |
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individuals that exhibit risk factors, such as high-risk hematological patients. |
Price et al. |
2015 |
Pest Management Science |
Fusarium sp. exhibits mechanisms that contribute to the acquisition of resistance to |
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even the most diverse antifungal agents. These mechanisms include changes in the |
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amino acid sequence, overexpression of the CYP51 gene, and overexpression of |
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genes that encode efflux pumps. |
van Diepeningen et al. |
2015a |
Current Fungal Infection |
Different Fusarium species have been associated with local or invasive infections in both |
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Report |
immunosuppressed and immunocompetent individuals. |
van Diepeningen et al. |
2015b |
Mycoses |
Members of the F. solani complex are the most common and virulent, followed by F.
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oxysporum, F. fujikuroi, and F. moniliforme. |
Al-Hatmi et al. |
2016a |
Emerging Microbes & Infections |
Treatment given for Fusarium infections varies according to the site of infection. |
Al-Hatmi et al. |
2016b |
The Journal of Antimicrobial |
In vitro combined use of natamycin and voriconazole was found to be synergistic |
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Chemotherapy |
against most Fusarium strains, thereby significantly reducing the concentrations |
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required to inhibit fungal growth. |
Dalhoff |
2016 |
Journal of Global Antimicrobial |
Fusariosis is difficult to treat and the use of antimycotics in agriculture and horticulture |
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Resistance |
facilitates the acquisition of antifungal resistance. |
Espinel-Ingroff et al. |
2016 |
Antimicrobial Agents and |
A cutoff point for minimum inhibitory concentration values for various Fusarium species |
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Chemotherapy |
was proposed based on laboratory results. |
Ribas et al. |
2016 |
Brazilian Journal of |
Environmental isolates of Fusarium spp. could acquire resistance due to previous |
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Microbiology |
exposure to fungicides that are used agriculturally in the field. |
Al-Hatmi et al. |
2017 |
Journal of Fungi |
No standardization is established regarding MIC cut points for Fusarium, which renders |
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it difficult to classify the susceptibility profile of isolates. |
Batista et al. |
2017 |
Chemistry Select |
New chemical molecules exhibited low MICs (high potency) against Fusarium spp. and |
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reduced toxicity with promising applicability in the biological and industrial fields. |
Fuentefria et al. |
2017 |
Letters in Applied |
Combination therapy have been an important alternative for combating Fusarium species |
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Microbiology |
. |
Kolar et al. |
2017 |
Investigative Ophthalmology & |
Dectin-1 and TLR2 play an important role in the regulation of F. solani-induced AMP |
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Visual Science |
expression in corneal epithelial cells, facilitating the eradication of fungal pathogens. |
Al-Hatmi et al. |
2018 |
International Journal of |
New identification tools for Fusarium spp. to aid in selecting the most appropriate treatment |
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Antimicrobial Agents |
. |
Bashir et al. |
2018 |
Environmental Science and |
Evaluated various concentrations of fungicides used to combat fusariosis in plant. The |
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Pollution Research |
use of carbendazim significantly reduced the incidence of disease by 49.7% after 40 |
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days of application. |
Homa et al. |
2018 |
Frontiers in Microbiology |
F. falciforme was the most prevalent species of FSSC in South India. Susceptibility and |
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virulence of clinical and environmental isolates were similar. |