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Short Communication • Rev. Soc. Bras. Med. Trop. 50 (02) • Mar-Apr 2017 • https://doi.org/10.1590/0037-8682-0371-2016   copy

Prevalence and antimicrobial susceptibility of non-fermenting Gram-negative bacilli isolated from clinical samples at a tertiary care hospital

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstract

INTRODUCTION:

We compared the prevalence and antimicrobial susceptibility of non-fermenting gram-negative bacilli (NFGNB) isolated from clinical samples at a Brazilian tertiary care hospital in 2008 and 2013.

METHODS:

Collected data included patient’s name, age, sex, inpatient unit, laboratory record number, type of biological material, culture test result, and antimicrobial susceptibility of isolated strains.

RESULTS:

Out of 19,112 culture tests analyzed, 926 (4.8%) were positive for NFGNB. Among these, 45.2% were metallo-beta-lactamase (MBL) producing strains.

CONCLUSION:

Between 2008 and 2013, the number of MBL-producing NFGNB isolates increased by 21.5%, which was accompanied by a consequent reduction in susceptibility to antimicrobials.

Keywords:
Bacterial resistance; Metallo-beta-lactamase; Nosocomial infections

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