Abstract
INTRODUCTION:
The emergence of New Delhi metallo-β-lactamase (NDM) is concernig because it reduces the antibiotic therapy options for bacterial infections.
METHODS:
Resistant and virulent genes from an isolate of Klebsiella pneumoniae derived from a patient with sepsis in a hospital in Recife-PE, Brazil, were investigated using PCR and DNA sequencing.
RESULTS:
blaNDM-1, aac(6’)-Ib-cr and acrB resistance genes, and cps and mrkD virulence genes were detected.
CONCLUSIONS
To our knowledge, this is the first report on bla NDM-1 in Recife-PE. This detection alerts researchers to the need to control the spread of bla NDM-1 resistance gene by this bacterium in Brazil.
Keywords:
bla
NDM-1
; Klebsiella pneumoniae; Resistance; Virulence