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Hybrid capture II and PapilloCheck® tests for detection of anal high-risk human papillomavirus

Introduction

This study evaluated the level of concordance between hybrid capture II (HCII) and PapilloCheck® for the detection of high-risk human papillomavirus (HPV) in anal samples.

Methods

Anal cell samples collected from 42 human immunodeficiency virus (HIV)+ patients were analyzed.

Results

Considering only the 13 high-risk HPV types that are detectable by both tests, HCII was positive for 52.3% of the samples, and PapilloCheck® was positive for 52.3%. The level of concordance was 80.9% (Kappa = 0.61).

Conclusions

Good concordance was observed between the tests for the detection of high-risk HPV.

Human papillomavirus; PapilloCheck®; Hybrid capture II


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